prikaz prve stranice dokumenta Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease
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Scientific paper - Original scientific paper
Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease
Kardiologia Polska, 74 (2016), 5; 461-468. urn:nbn:hr:184:069493
Boban, Marko; Peršić, Viktor; Petričević, Mate; Biočina, Bojan; Sipic, Tomislav; Pehar-Pejčnovic, Vesna; Balen, Sanja; Žulj, Marinko; Včev, Aleksandar

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Boban, M., Peršić, V., Petričević, M., Biočina, B., Sipic, T., Pehar Pejčnovic, V. ... Včev, A. (2016). Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease. Kardiologia Polska, 74. (5), 461-468. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:069493

Boban, Marko, et al. "Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease." Kardiologia Polska, vol. 74, no. 5, 2016, pp. 461-468. https://urn.nsk.hr/urn:nbn:hr:184:069493

Boban, Marko, Viktor Peršić, Mate Petričević, Bojan Biočina, Tomislav Sipic, Vesna Pehar Pejčnovic, Sanja Balen, Marinko Žulj and Aleksandar Včev. "Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease." Kardiologia Polska 74, no. 5 (2016): 461-468. https://urn.nsk.hr/urn:nbn:hr:184:069493

Boban, M., et al. (2016) 'Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease', Kardiologia Polska, 74(5), pp. 461-468. Available at: https://urn.nsk.hr/urn:nbn:hr:184:069493 (Accessed 01 January 2025)

Boban M, Peršić V, Petričević M, Biočina B, Sipic T, Pehar Pejčnovic V, and sur.. Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease. Kardiologia Polska [Internet]. 2016 [cited 2025 January 01];74(5):461-468. Available at: https://urn.nsk.hr/urn:nbn:hr:184:069493

M. Boban, et al., "Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease", Kardiologia Polska, vol. 74, no. 5, pp. 461-468, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:069493. [Accessed: 01 January 2025]

Metadata
Title (english)Connections between nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischaemic and valvular heart disease
AuthorMarko Boban
AuthorViktor Peršić
AuthorMate Petričević
AuthorBojan Biočina
AuthorTomislav Sipic
AuthorVesna Pehar-Pejčnovic
AuthorSanja Balen
MBZ: 236875
AuthorMarinko Žulj
AuthorAleksandar Včev
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Abstract Background: Multiple and yet uncertain connections exist between cardiovascular diseases and the nutritional status of patients, particularly in relation to cardiovascular treatments. Proton pump inhibitors (PPI) are among the most commonly used group of drugs. Aim: To analyse utilisation of PPI in association with nutritional risk of patients scheduled for rehabilitation after treatment for ischaemic and valvular heart disease. Methods: Retrospective analyses on a consecutive sample of patients, which included drug utilisation of PPI and nutritional risk screening, using a standardised NRS-2002 tool. The patients (n = 536) were divided into groups based on previous cardiovascular treatments and use of PPI. Results: Nearly half of the patients (244, 46.1%) had PPI in their chronic therapy despite the clinically negligible prevalence of conditions that are their fundamental indications. The odds for using PPI in patients with increased nutritional risk, estimated by logistic regression, were 3.34 (95% confidence intervals [CI] 2.26–4.94), p < 0.001. Receiver operating curve analyses also revealed significant differences of PPI utilisation in connection with NRS-2002 > 3: positive likelihood-ratio (LR) 2.35 (95% CI 2.10–2.60); negative LR 0.46 (95% CI 0.4–0.6); area under the curve (AUC) 0.720; p < 0.001; as well as the percentage weigh loss history > 6.36% (positive LR 2.22 [95% CI 2.00–2.50]; negative LR 0.41 [95% CI 0.30–0.50]; AUC 0.707; p < 0.001). Conclusions: Utilisation of PPI was found to be of relatively high prevalence and significantly associated with parameters of nutritional risk screening. Furthermore, it was in correlation with the age of patients and the existence of chronic kidney dis ease, which are well-established predispositions for poor nutritional status. Nutritional risk seems to be additionally negatively challenged by utilisation of PPI due to gastric malabsorption and anaemia.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleKardiologia Polska
Numberingvol. 74, no. 5, pp. 461-468
e-ISSN0022-9032
URN:NBNurn:nbn:hr:184:069493
Publication2016
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-09-17 20:31:26