prikaz prve stranice dokumenta Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids
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Scientific paper - Original scientific paper
Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids
Personalized Medicine, 16 (2019), 2; 171-184. https://doi.org/10.2217/pme-2018-0116
Bach-Rojecky, Lidija; Vađunec, Dalia; Žunić, Katarina; Kurija, Jelena; Šipicki, Sara; Gregg, Ryan; Mikula, Ivan; Primorac, Dragan

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Bach Rojecky, L., Vađunec, D., Žunić, K., Kurija, J., Šipicki, S., Gregg, R. ... Primorac, D. (2019). Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids. Personalized Medicine, 16. (2), 171-184. doi: 10.2217/pme-2018-0116

Bach Rojecky, Lidija, et al. "Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids." Personalized Medicine, vol. 16, no. 2, 2019, pp. 171-184. https://doi.org/10.2217/pme-2018-0116

Bach Rojecky, Lidija, Dalia Vađunec, Katarina Žunić, Jelena Kurija, Sara Šipicki, Ryan Gregg, Ivan Mikula and Dragan Primorac. "Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids." Personalized Medicine 16, no. 2 (2019): 171-184. https://doi.org/10.2217/pme-2018-0116

Bach Rojecky, L., et al. (2019) 'Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids', Personalized Medicine, 16(2), pp. 171-184. doi: 10.2217/pme-2018-0116

Bach Rojecky L, Vađunec D, Žunić K, Kurija J, Šipicki S, Gregg R, and sur.. Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids. Personalized Medicine [Internet]. 2019 [cited 2024 November 28];16(2):171-184. doi: 10.2217/pme-2018-0116

L. Bach Rojecky, et al., "Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids", Personalized Medicine, vol. 16, no. 2, pp. 171-184, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:257516. [Accessed: 28 November 2024]

Metadata
Title (english)Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids
AuthorLidija Bach-Rojecky
MBZ: 216204
AuthorDalia Vađunec
AuthorKatarina Žunić
AuthorJelena Kurija
AuthorSara Šipicki
AuthorRyan Gregg
AuthorIvan Mikula
MBZ: 188391
AuthorDragan Primorac
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Abstract (english)
Successful pain management requires the delivery of analgesia with minimal risk of adverse drug reactions. Nonsteroidal anti- inflammatory drugs and opioids remain the mainstay of treatment for the majority of patients. Unfortunately, almost 50% of all patients experience inadequate pain relief and serious side effects. Allelic variants in genes coding for target proteins, transporters and enzymes, which govern analgesic drugs action and their fate in the organism, might explain inter-individual variability in pain severity and in drug-induced pain relief and toxicities. Additionally, it seems that epigenetic changes contribute to the highly variable response to pain treatment. Therefore, pharmacogenomic testing might be a valuable tool for personalization of pain treatment, with a multidisciplinary team approach involved
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titlePersonalized Medicine
Numberingvol. 16, no. 2, pp. 171-184
p-ISSN1741-0541
DOIhttps://doi.org/10.2217/pme-2018-0116
URN:NBNurn:nbn:hr:184:257516
Publication2019
Document URLhttp://bib.irb.hr/1050150
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2022-02-14 12:47:58