prikaz prve stranice dokumenta Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids
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Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids
Personalized Medicine, 16 (2019), 2; 171-184. https://doi.org/10.2217/pme-2018-0116
Bach-Rojecky, Lidija; Vađunec, Dalia; Žunić, Katarina; Kurija, Jelena; Šipicki, Sara; Gregg, Ryan; Mikula, Ivan; Primorac, Dragan

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

Bach Rojecky, L., Vađunec, D., Žunić, K., Kurija, J., Šipicki, S., Gregg, R. ... Primorac, D. (2019). Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids. Personalized Medicine, 16. (2), 171-184. doi: 10.2217/pme-2018-0116

Bach Rojecky, Lidija, et al. "Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids." Personalized Medicine, vol. 16, br. 2, 2019, str. 171-184. https://doi.org/10.2217/pme-2018-0116

Bach Rojecky, Lidija, Dalia Vađunec, Katarina Žunić, Jelena Kurija, Sara Šipicki, Ryan Gregg, Ivan Mikula i Dragan Primorac. "Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids." Personalized Medicine 16, br. 2 (2019): 171-184. https://doi.org/10.2217/pme-2018-0116

Bach Rojecky, L., et al. (2019) 'Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids', Personalized Medicine, 16(2), str. 171-184. doi: 10.2217/pme-2018-0116

Bach Rojecky L, Vađunec D, Žunić K, Kurija J, Šipicki S, Gregg R, i sur.. Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids. Personalized Medicine [Internet]. 2019. [pristupljeno 12.05.2024.];16(2):171-184. doi: 10.2217/pme-2018-0116

L. Bach Rojecky, et al., "Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids", Personalized Medicine, vol. 16, br. 2, str. 171-184, 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:257516. [Citirano: 12.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:257516
Podaci o radu
Naslov (engleski)Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti- inflammatory drugs and opioids
AutorLidija Bach-Rojecky
MBZ: 216204
AutorDalia Vađunec
AutorKatarina Žunić
AutorJelena Kurija
AutorSara Šipicki
AutorRyan Gregg
AutorIvan Mikula
MBZ: 188391
AutorDragan Primorac
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku biologiju i genetiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Sažetak (engleski)
Successful pain management requires the delivery of analgesia with minimal risk of adverse drug reactions. Nonsteroidal anti- inflammatory drugs and opioids remain the mainstay of treatment for the majority of patients. Unfortunately, almost 50% of all patients experience inadequate pain relief and serious side effects. Allelic variants in genes coding for target proteins, transporters and enzymes, which govern analgesic drugs action and their fate in the organism, might explain inter-individual variability in pain severity and in drug-induced pain relief and toxicities. Additionally, it seems that epigenetic changes contribute to the highly variable response to pain treatment. Therefore, pharmacogenomic testing might be a valuable tool for personalization of pain treatment, with a multidisciplinary team approach involved
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPersonalized Medicine
Brojčani podacivol. 16, br. 2, str. 171-184
p-ISSN1741-0541
DOIhttps://doi.org/10.2217/pme-2018-0116
URN:NBNurn:nbn:hr:184:257516
Datum objave publikacije2019
URL dokumentahttp://bib.irb.hr/1050150
Vrsta resursaTekst
Prava pristupaZatvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-14 12:47:58