prikaz prve stranice dokumenta Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey
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Scientific paper - Original scientific paper
Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey
International Journal of Cardiology, 272 (2018); 20-25. https://doi.org/10.1016/j.ijcard.2018.06.104
De Smedt, Delphine; Annemans, Lieven; De Backer, Guy; Kotseva, Kornelia; Rydèn, Lars; Wood, David; Amouyel, Philippe; Bruthans, Jan; Cifkova, Renata; De Sutter, Johan; Dolzhenko, Marina; Erglis, Andrejs; Gotcheva, Nina; Gyberg, Viveca; Laucevicius, Aleksandras; Lovic, Dragan; Oganov, Rafael; Pajak, Andrzej; Pogosova, Nana; Reiner, Željko; Stagmo, Martin; De Bacquer, Dirk More authors...

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Cite this document

De Smedt, D., Annemans, L., De Backer, G., Kotseva, K., Rydèn, L., Wood, D. ... De Bacquer, D. (2018). Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey. International Journal of Cardiology, 272., 20-25. doi: 10.1016/j.ijcard.2018.06.104

De Smedt, Delphine, et al. "Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey." International Journal of Cardiology, vol. 272, 2018, pp. 20-25. https://doi.org/10.1016/j.ijcard.2018.06.104

De Smedt, Delphine, Lieven Annemans, Guy De Backer, Kornelia Kotseva, Lars Rydèn, David Wood, Philippe Amouyel, et al. "Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey." International Journal of Cardiology 272 (2018): 20-25. https://doi.org/10.1016/j.ijcard.2018.06.104

De Smedt, D., et al. (2018) 'Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey', International Journal of Cardiology, 272, pp. 20-25. doi: 10.1016/j.ijcard.2018.06.104

De Smedt D, Annemans L, De Backer G, Kotseva K, Rydèn L, Wood D, and sur.. Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey. International Journal of Cardiology [Internet]. 2018 [cited 2024 December 02];272:20-25. doi: 10.1016/j.ijcard.2018.06.104

D. De Smedt, et al., "Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey", International Journal of Cardiology, vol. 272, pp. 20-25, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:751161. [Accessed: 02 December 2024]

Metadata
Title (english)Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey
AuthorDelphine De Smedt
AuthorLieven Annemans
AuthorGuy De Backer
AuthorKornelia Kotseva
AuthorLars Rydèn
AuthorDavid Wood
AuthorPhilippe Amouyel
AuthorJan Bruthans
AuthorRenata Cifkova
AuthorJohan De Sutter
AuthorMarina Dolzhenko
AuthorAndrejs Erglis
AuthorNina Gotcheva
AuthorViveca Gyberg
AuthorAleksandras Laucevicius
AuthorDragan Lovic
AuthorRafael Oganov
AuthorAndrzej Pajak
AuthorNana Pogosova
AuthorŽeljko Reiner
AuthorMartin Stagmo
AuthorDirk De Bacquer
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background: This study aims to assess the cost- effectiveness of optimized guideline adherence in patients with a history of coronary heart disease. Methods: An individual-based decision tree model was developed using the SMART risk score tool which estimates the 10-year risk for recurrent vascular events in patients with manifest cardiovascular disease (CVD). Analyses were based on the EUROASPIRE IV survey. Outcomes were expressed as an incremental cost- effectiveness ratio (ICER). Results: Data from 4663 patients from 13 European countries were included in the analyses. The mean estimated 10-year risk for a recurrent vascular event decreased from 20.13% to 18.61% after optimized guideline adherence. Overall, an ICER of 52, 968(sic)/QALY was calculated. The ICER lowered to 29, 093(sic)/QALY when only considering high- risk patients (>= 20%) with decreasing ICERs in higher risk patients. Also, a dose-response relationship was seen with lower ICERs in older patients and in those patients with higher risk reductions. A less stringent LDL target (<2.5 mmol/L vs. <1.8 mmol/L) lowered the ICER to 32, 591(sic)/QALY and intensifying cholesterol treatment in high-risk patients (>= 20%) instead of high-cholesterol patients lowered the ICER to 28, 064(sic)/QALY. An alternative method, applying risk reductions to the CVD events instead of applying risk reductions to the risk factors lowered the ICER to 31, 509(sic)/QALY. Conclusion: Depending on the method used better or worse ICERs were found. In addition, optimized guidelines adherence is more cost- effective in higher risk patients, in patients with higher risk reductions and when using a less strict LDL-C target. Current analyses advice to maximize guidelines adherence in particular patient subgroups.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Cardiology
Numberingvol. 272, pp. 20-25
p-ISSN0167-5273
DOIhttps://doi.org/10.1016/j.ijcard.2018.06.104
URN:NBNurn:nbn:hr:184:751161
Publication2018
Document URLhttp://bib.irb.hr/1050156
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2022-03-16 15:23:15