prikaz prve stranice dokumenta Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey
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Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey
International Journal of Cardiology, 272 (2018); 20-25. https://doi.org/10.1016/j.ijcard.2018.06.104
De Smedt, Delphine; Annemans, Lieven; De Backer, Guy; Kotseva, Kornelia; Rydèn, Lars; Wood, David; Amouyel, Philippe; Bruthans, Jan; Cifkova, Renata; De Sutter, Johan; Dolzhenko, Marina; Erglis, Andrejs; Gotcheva, Nina; Gyberg, Viveca; Laucevicius, Aleksandras; Lovic, Dragan; Oganov, Rafael; Pajak, Andrzej; Pogosova, Nana; Reiner, Željko; Stagmo, Martin; De Bacquer, Dirk Više autora...

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

De Smedt, D., Annemans, L., De Backer, G., Kotseva, K., Rydèn, L., Wood, D. ... De Bacquer, D. (2018). Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey. International Journal of Cardiology, 272., 20-25. doi: 10.1016/j.ijcard.2018.06.104

De Smedt, Delphine, et al. "Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey." International Journal of Cardiology, vol. 272, 2018, str. 20-25. https://doi.org/10.1016/j.ijcard.2018.06.104

De Smedt, Delphine, Lieven Annemans, Guy De Backer, Kornelia Kotseva, Lars Rydèn, David Wood, Philippe Amouyel, et al. "Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey." International Journal of Cardiology 272 (2018): 20-25. https://doi.org/10.1016/j.ijcard.2018.06.104

De Smedt, D., et al. (2018) 'Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey', International Journal of Cardiology, 272, str. 20-25. doi: 10.1016/j.ijcard.2018.06.104

De Smedt D, Annemans L, De Backer G, Kotseva K, Rydèn L, Wood D, i sur.. Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey. International Journal of Cardiology [Internet]. 2018. [pristupljeno 12.05.2024.];272:20-25. doi: 10.1016/j.ijcard.2018.06.104

D. De Smedt, et al., "Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey", International Journal of Cardiology, vol. 272, str. 20-25, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:751161. [Citirano: 12.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:751161
Podaci o radu
Naslov (engleski)Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey
AutorDelphine De Smedt
AutorLieven Annemans
AutorGuy De Backer
AutorKornelia Kotseva
AutorLars Rydèn
AutorDavid Wood
AutorPhilippe Amouyel
AutorJan Bruthans
AutorRenata Cifkova
AutorJohan De Sutter
AutorMarina Dolzhenko
AutorAndrejs Erglis
AutorNina Gotcheva
AutorViveca Gyberg
AutorAleksandras Laucevicius
AutorDragan Lovic
AutorRafael Oganov
AutorAndrzej Pajak
AutorNana Pogosova
AutorŽeljko Reiner
AutorMartin Stagmo
AutorDirk De Bacquer
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: This study aims to assess the cost- effectiveness of optimized guideline adherence in patients with a history of coronary heart disease. Methods: An individual-based decision tree model was developed using the SMART risk score tool which estimates the 10-year risk for recurrent vascular events in patients with manifest cardiovascular disease (CVD). Analyses were based on the EUROASPIRE IV survey. Outcomes were expressed as an incremental cost- effectiveness ratio (ICER). Results: Data from 4663 patients from 13 European countries were included in the analyses. The mean estimated 10-year risk for a recurrent vascular event decreased from 20.13% to 18.61% after optimized guideline adherence. Overall, an ICER of 52, 968(sic)/QALY was calculated. The ICER lowered to 29, 093(sic)/QALY when only considering high- risk patients (>= 20%) with decreasing ICERs in higher risk patients. Also, a dose-response relationship was seen with lower ICERs in older patients and in those patients with higher risk reductions. A less stringent LDL target (<2.5 mmol/L vs. <1.8 mmol/L) lowered the ICER to 32, 591(sic)/QALY and intensifying cholesterol treatment in high-risk patients (>= 20%) instead of high-cholesterol patients lowered the ICER to 28, 064(sic)/QALY. An alternative method, applying risk reductions to the CVD events instead of applying risk reductions to the risk factors lowered the ICER to 31, 509(sic)/QALY. Conclusion: Depending on the method used better or worse ICERs were found. In addition, optimized guidelines adherence is more cost- effective in higher risk patients, in patients with higher risk reductions and when using a less strict LDL-C target. Current analyses advice to maximize guidelines adherence in particular patient subgroups.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Cardiology
Brojčani podacivol. 272, str. 20-25
p-ISSN0167-5273
DOIhttps://doi.org/10.1016/j.ijcard.2018.06.104
URN:NBNurn:nbn:hr:184:751161
Datum objave publikacije2018
URL dokumentahttp://bib.irb.hr/1050156
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-03-16 15:23:15