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master's thesis
Volumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka
Zagreb: University of Zagreb, School of Medicine, 2014. urn:nbn:hr:105:153322
Mandić, Dora
University of Zagreb
School of Medicine
Department of Radiology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Mandić, D. (2014). Volumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:153322

Mandić, Dora. "Volumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka." Master's thesis, University of Zagreb, School of Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:105:153322

Mandić, Dora. "Volumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka." Master's thesis, University of Zagreb, School of Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:105:153322

Mandić, D. (2014). 'Volumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka', Master's thesis, University of Zagreb, School of Medicine, accessed 25 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:153322

Mandić D. Volumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2014 [cited 2024 December 25] Available at: https://urn.nsk.hr/urn:nbn:hr:105:153322

D. Mandić, "Volumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2014. Available at: https://urn.nsk.hr/urn:nbn:hr:105:153322

Metadata
TitleVolumetrijska analiza razvoja kortikalne i subkortikalne sive tvari kod čovjeka
Title (english)Volumetric analysis of cortical and subcortical gray matter development in humans
AuthorDora Mandić
MentorMilan Radoš (mentor)
Committee memberGoran Šimić (predsjednik povjerenstva)
Committee memberMario Vukšić (član povjerenstva)
Committee memberMilan Radoš (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Radiology)
Zagreb
Defense date and country2014-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Radiology
Abstract
Tijekom razvoja mozga događaju se značajne promjene volumena različitih dijelova mozga i njihovih omjera. Najveće promjene događaju se u prvim godinama života. Poznavanje normalne dinamike razvoja kortikalne i subkortikalne sive tvari iznimno je bitno jer omogućuje rano prepoznavanje poremećenog razvoja mozga te time pruža priliku za raniju primjenu terapijskih procedura. U ovoj studiji analizirali smo promjene volumena moždanog tkiva na MR snimkama dobivenim snimanjem sedmero zdrave djece u dvama vremenskim razdobljima. Ispitanici su podijeljeni u dvije dobne skupine dojenčad i djeca u dobi od dvije godine. Rezultati ove studije pokazali su da u prvim dvjema godinama života postoji značajan rast volumena kortikalne sive tvari i talamusa. Za razliku od toga, ukupni volumen bazalnih ganglija ne pokazuje statistički značajnu razliku volumena u ovom razdoblju. Zaključak ove studije je da se značajan rast volumena kortikalne sive tvari i talamusa događa postnatalno u prvim godinama života, dok se povećanje volumena bazalnih ganglija odvija dominantno u prenatalnom razdoblju.
Abstract (english)
In the course of brain development significant changes can be observed in the volumes of different brain parts and their ratios. The major changes are observed during the first few years of life. It is essential to be acquainted with the normal dynamic of cortical and subcortical grey matter development because it allows early detection of defective brain development thus providing an opportunity for earlier treatment. Therefore, it is vital to determine the normative values in order to detect certain impairment in the growth of the brain at an early stage and to provide proper treatment. In this study, we have analyzed the changes in the brain tissue volume in MR images that were obtained from 7 normal children in two different age groups: infants and two-year-old children. The results of this study showed a significant increase in the volume of cortical gray matter and thalamus in the first two years of life. Contrary to this finding, the basal ganglia did not show a statistically significant difference in volume in the analyzed age groups. The conclusion of this study is that the significant changes in the volume growth of cortical gray matter and thalamus occur postnatally, during the first few years of life, while the major changes in the volume growth of basal ganglia occur prenatally.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:153322
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2015-09-14 09:55:54