prikaz prve stranice dokumenta Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report
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Scientific paper - Case study
Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report
Collegium Antropologicum, 36 (2012), S. 2; 219-221. urn:nbn:hr:105:262013
Vukasović, Anamarija; Kusačić Kuna, Sanja; Trutin Ostović, Karmen; Prgomet, Drago; Banek, Tomislav

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Vukasović, A., Kusačić Kuna, S., Trutin Ostović, K., Prgomet, D. & Banek, T. (2012). Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report . Collegium Antropologicum, 36. (S. 2), 219-221. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:262013

Vukasović, Anamarija, et al. "Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report ." Collegium Antropologicum, vol. 36, no. S. 2, 2012, pp. 219-221. https://urn.nsk.hr/urn:nbn:hr:105:262013

Vukasović, Anamarija, Sanja Kusačić Kuna, Karmen Trutin Ostović, Drago Prgomet and Tomislav Banek. "Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report ." Collegium Antropologicum 36, no. S. 2 (2012): 219-221. https://urn.nsk.hr/urn:nbn:hr:105:262013

Vukasović, A., et al. (2012) 'Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report ', Collegium Antropologicum, 36(S. 2), pp. 219-221. Available at: https://urn.nsk.hr/urn:nbn:hr:105:262013 (Accessed 29 November 2024)

Vukasović A, Kusačić Kuna S, Trutin Ostović K, Prgomet D, Banek T. Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report . Collegium Antropologicum [Internet]. 2012 November [cited 2024 November 29];36(S. 2):219-221. Available at: https://urn.nsk.hr/urn:nbn:hr:105:262013

A. Vukasović, S. Kusačić Kuna, K. Trutin Ostović, D. Prgomet and T. Banek, "Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report ", Collegium Antropologicum, vol. 36, no. S. 2, pp. 219-221, November 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:262013. [Accessed: 29 November 2024]

Metadata
Title (english)Diffuse sclerosing variant of thyroid carcinoma presenting as Hashimoto thyroiditis: a case report
Title (croatian)Difuzno sklerozirajući oblik papilarnog karcinoma štitnjače nalik Hashimoto tireoiditisu: prikaz slučaja
AuthorAnamarija Vukasović
AuthorSanja Kusačić Kuna
AuthorKarmen Trutin Ostović
AuthorDrago Prgomet
AuthorTomislav Banek
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of report is to present a case of a rare diffuse sclerosing variant of a papillary thyroid carcinoma. A 15-year old girl referred for ultrasound examination because of painless thyroid swelling lasting 10 days before. An ultrasound of the neck showed diffusely changed thyroid parenchyma, without nodes, looking as lymphocytic thyroiditis Hashimoto at first, but with snow-storm appearance, predominantly in the right lobe. Positive thyroid peroxidase antibodies (TPO-AT) also suggested Hashimoto thyroiditis. Repeated US-FNAB (fine needle-aspiration biopsy) of the right lobe revealed diffuse sclerosing variant of papillary thyroid carcinoma and patient underwent total thyreoidectomy. Patohistologic finding confirmed diffuse sclerosing variant of a papillary thyroid carcinoma in the both thyroid lobes and several metastatic lymph nodes. Two months later patient recived radioablative therapy with 3700 MBq (100 mCi) of 1-131 followed by levothyroxine replacement. At the moment, patient is without evidence of local or distant metastases and next regular control is scheduled in 6 months. In conclusion, a diffuse sclerosing variant is rare form of papillary thyroid carcinoma that echographically looks similar to Hashimoto thyroiditis and sometimes could be easily overlooked.
Abstract (croatian)
Opisan je slučaj petnaestogodišnje djevojke upućene na ultrazvučni pregled zbog bezbolnog zadebljanja štitnjače nastalog 10-ak dana prije dolaska na obradu. Bolesnica je bila eutiroidna uz povišena antitijela na peroksidazu (TPO- -At) što je postavilo sumnju na postojanje autoimunog limfocitnog tireoiditisa. Ultrazvučnim pregledom verificirane su difuzne promjene ehostukture u parenhimu oba režnja štitnjače nalik kroničnom limfocitnom Hashimoto tireoiditisu. Međutim, obzirom na prisutnost punktiformnih kalcifikata unutar desnog režnja štitnjače, ipak je, unatoč nepostojanju nodoznih promjena u štitnjači učinjena citološka punkcija pod kontrolom ultrazvuka, te je potvrđena sumnja na difuzno sklerozirajući oblik papilarnog karcinoma u desnom režnju štitnjače. Učinjena je totalna tireoidektomija sa selektivnom disekcijom limfnih čvorova na vratu, a patohistološki nalaz je potvrdio dijagnozu difuzno sklerozirajućeg karcinoma u desnom režnju štitnjače s fokalnim žarištima tumora i u lijevom režnju, infiltraciju kapsule štitnjače, kao i više pozitivnih limfnih čvorova obostrano na vratu. Dva mjeseca kasnije bolesnici je aplicirana radiojodna ablacija sa 3700 MBq (100 mCi) I-131, a potom je stavljena na supresijsku terapiju L-tiroksinom. U ovom trenutku bolesnica je bez evidentnih znakova lokalnih ili distalnih metastaza i očekuje redovitu kontrolnu obradu predviđenu za oko 6 mjeseci. Kod mlađih bolesnika sa bezbolnim povećanjem štitnjače i promjenama ehostrukture u smislu kroničnog tireoiditisa Hashimoto, ali sa difuznim punktiformnim kalcifikatima unutar režnjeva potrebno je svakako imati u vidu i ovu rijetku vrstu papilarnog karcinoma. Stoga je u takvim slučajevima unatoč nepostojanju nodoznih promjena neophodno učiniti ciljanu citološku punkciju koja nam pomaže u postavljanju točne dijagnoze.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 36, no. S. 2, pp. 219-221
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:262013
Publication2012-11
Document URLhttps://hrcak.srce.hr/96610
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:47:04