prikaz prve stranice dokumenta Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder
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Scientific paper - Original scientific paper
Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder
Annals of Clinical Biochemistry, 52 (2015), 1; 95-104. https://doi.org/10.1177/0004563214528882
Borovac Štefanović, Leda; Kalinić, Dubravka; Mimica, Ninoslav; Beer Ljubić, Blanka; Aladrović, Jasna; Mandelsamen Perica, Marina; Čurić, Maja; Folnegović Grošić, Petra; Delaš, Ivančica

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Borovac Štefanović, L., Kalinić, D., Mimica, N., Beer Ljubić, B., Aladrović, J., Mandelsamen Perica, M. ... Delaš, I. (2015). Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder. Annals of Clinical Biochemistry, 52. (1), 95-104. doi: 10.1177/0004563214528882

Borovac Štefanović, Leda, et al. "Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder." Annals of Clinical Biochemistry, vol. 52, no. 1, 2015, pp. 95-104. https://doi.org/10.1177/0004563214528882

Borovac Štefanović, Leda, Dubravka Kalinić, Ninoslav Mimica, Blanka Beer Ljubić, Jasna Aladrović, Marina Mandelsamen Perica, Maja Čurić, Petra Folnegović Grošić and Ivančica Delaš. "Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder." Annals of Clinical Biochemistry 52, no. 1 (2015): 95-104. https://doi.org/10.1177/0004563214528882

Borovac Štefanović, L., et al. (2015) 'Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder', Annals of Clinical Biochemistry, 52(1), pp. 95-104. doi: 10.1177/0004563214528882

Borovac Štefanović L, Kalinić D, Mimica N, Beer Ljubić B, Aladrović J, Mandelsamen Perica M, and sur.. Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder. Annals of Clinical Biochemistry [Internet]. 2015 January [cited 2025 January 05];52(1):95-104. doi: 10.1177/0004563214528882

L. Borovac Štefanović, et al., "Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder", Annals of Clinical Biochemistry, vol. 52, no. 1, pp. 95-104, January 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:270632. [Accessed: 05 January 2025]

Metadata
Title (english)Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder
AuthorLeda Borovac Štefanović
AuthorDubravka Kalinić
AuthorNinoslav Mimica
AuthorBlanka Beer Ljubić
AuthorJasna Aladrović
AuthorMarina Mandelsamen Perica
AuthorMaja Čurić
AuthorPetra Folnegović Grošić
AuthorIvančica Delaš
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
BACKGROUND: The aim of this study was to measure the parameters of oxidative stress in the blood of patients with post-traumatic stress disorder. ----- METHODS: The study included 80 male war veterans who participated actively in the Homeland war in Croatia. Volunteers were divided into two groups: 50 veterans diagnosed with post-traumatic stress disorder and 30 without diagnosis. The self-assessment Hospital Anxiety and Depression Scale and the Beck Depression Inventory were used to detect the severity of depression and anxiety in the post-traumatic stress disorder patients. Catalytic concentrations of superoxide dismutase and glutathione peroxidase in erythrocytes and the concentration of malondialdehyde in serum were measured spectrophotometrically. ----- RESULTS: Although the catalytic concentrations of erythrocyte superoxide dismutase and erythrocyte glutathione peroxidase were within the reference range for both groups, the values obtained for the post-traumatic stress disorder group were significantly lower (P<0.001). For serum malondialdehyde concentrations, no statistically significant differences between the groups were found. ----- CONCLUSIONS: Lower catalytic concentrations of erythrocyte superoxide dismutase and erythrocyte glutathione peroxidase in patients with post-traumatic stress disorder may indicate a weaker response to oxidative stress due to impaired enzyme activity and/or decreased synthesis. Conversely, no significant changes in serum malondialdehyde concentrations suggest a compensated balance and adaptive response to (oxidative) stress.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleAnnals of Clinical Biochemistry
Numberingvol. 52, no. 1, pp. 95-104
p-ISSN0004-5632
DOIhttps://doi.org/10.1177/0004563214528882
URN:NBNurn:nbn:hr:105:270632
Publication2015-01
Document URLhttps://doi.org/10.1177/0004563214528882
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:09:00