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Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder
Annals of Clinical Biochemistry, 52 (2015), 1; 95-104. https://doi.org/10.1177/0004563214528882
Borovac Štefanović, Leda; Kalinić, Dubravka; Mimica, Ninoslav; Beer Ljubić, Blanka; Aladrović, Jasna; Mandelsamen Perica, Marina; Čurić, Maja; Folnegović Grošić, Petra; Delaš, Ivančica

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Borovac Štefanović, L., Kalinić, D., Mimica, N., Beer Ljubić, B., Aladrović, J., Mandelsamen Perica, M. ... Delaš, I. (2015). Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder. Annals of Clinical Biochemistry, 52. (1), 95-104. doi: 10.1177/0004563214528882

Borovac Štefanović, Leda, et al. "Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder." Annals of Clinical Biochemistry, vol. 52, br. 1, 2015, str. 95-104. https://doi.org/10.1177/0004563214528882

Borovac Štefanović, Leda, Dubravka Kalinić, Ninoslav Mimica, Blanka Beer Ljubić, Jasna Aladrović, Marina Mandelsamen Perica, Maja Čurić, Petra Folnegović Grošić i Ivančica Delaš. "Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder." Annals of Clinical Biochemistry 52, br. 1 (2015): 95-104. https://doi.org/10.1177/0004563214528882

Borovac Štefanović, L., et al. (2015) 'Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder', Annals of Clinical Biochemistry, 52(1), str. 95-104. doi: 10.1177/0004563214528882

Borovac Štefanović L, Kalinić D, Mimica N, Beer Ljubić B, Aladrović J, Mandelsamen Perica M, i sur.. Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder. Annals of Clinical Biochemistry [Internet]. 01.2015. [pristupljeno 03.01.2025.];52(1):95-104. doi: 10.1177/0004563214528882

L. Borovac Štefanović, et al., "Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder", Annals of Clinical Biochemistry, vol. 52, br. 1, str. 95-104, Siječanj 2015. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:270632. [Citirano: 03.01.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:270632
Podaci o radu
Naslov (engleski)Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder
AutorLeda Borovac Štefanović
AutorDubravka Kalinić
AutorNinoslav Mimica
AutorBlanka Beer Ljubić
AutorJasna Aladrović
AutorMarina Mandelsamen Perica
AutorMaja Čurić
AutorPetra Folnegović Grošić
AutorIvančica Delaš
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
BACKGROUND: The aim of this study was to measure the parameters of oxidative stress in the blood of patients with post-traumatic stress disorder. ----- METHODS: The study included 80 male war veterans who participated actively in the Homeland war in Croatia. Volunteers were divided into two groups: 50 veterans diagnosed with post-traumatic stress disorder and 30 without diagnosis. The self-assessment Hospital Anxiety and Depression Scale and the Beck Depression Inventory were used to detect the severity of depression and anxiety in the post-traumatic stress disorder patients. Catalytic concentrations of superoxide dismutase and glutathione peroxidase in erythrocytes and the concentration of malondialdehyde in serum were measured spectrophotometrically. ----- RESULTS: Although the catalytic concentrations of erythrocyte superoxide dismutase and erythrocyte glutathione peroxidase were within the reference range for both groups, the values obtained for the post-traumatic stress disorder group were significantly lower (P<0.001). For serum malondialdehyde concentrations, no statistically significant differences between the groups were found. ----- CONCLUSIONS: Lower catalytic concentrations of erythrocyte superoxide dismutase and erythrocyte glutathione peroxidase in patients with post-traumatic stress disorder may indicate a weaker response to oxidative stress due to impaired enzyme activity and/or decreased synthesis. Conversely, no significant changes in serum malondialdehyde concentrations suggest a compensated balance and adaptive response to (oxidative) stress.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaAnnals of Clinical Biochemistry
Brojčani podacivol. 52, br. 1, str. 95-104
p-ISSN0004-5632
DOIhttps://doi.org/10.1177/0004563214528882
URN:NBNurn:nbn:hr:105:270632
Datum objave publikacije2015-01
URL dokumentahttps://doi.org/10.1177/0004563214528882
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 08:09:00