prikaz prve stranice dokumenta Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002
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Scientific paper - Original scientific paper
Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002
Collegium Antropologicum, 31 (2007), 2; 535-540. urn:nbn:hr:105:956718
Vrbanec, Damir; Petričević, Branka

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Vrbanec, D. & Petričević, B. (2007). Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002. Collegium Antropologicum, 31. (2), 535-540. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:956718

Vrbanec, Damir and Branka Petričević. "Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002." Collegium Antropologicum, vol. 31, no. 2, 2007, pp. 535-540. https://urn.nsk.hr/urn:nbn:hr:105:956718

Vrbanec, Damir and Branka Petričević. "Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002." Collegium Antropologicum 31, no. 2 (2007): 535-540. https://urn.nsk.hr/urn:nbn:hr:105:956718

Vrbanec, D. and Petričević, B. (2007) 'Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002', Collegium Antropologicum, 31(2), pp. 535-540. Available at: https://urn.nsk.hr/urn:nbn:hr:105:956718 (Accessed 29 November 2024)

Vrbanec D, Petričević B. Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002. Collegium Antropologicum [Internet]. 2007 June [cited 2024 November 29];31(2):535-540. Available at: https://urn.nsk.hr/urn:nbn:hr:105:956718

D. Vrbanec and B. Petričević, "Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002", Collegium Antropologicum, vol. 31, no. 2, pp. 535-540, June 2007. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:956718. [Accessed: 29 November 2024]

Metadata
Title (english)Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002
AuthorDamir Vrbanec
AuthorBranka Petričević
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of this study was to gain insight of the breast cancer hormone receptor status of our patients, its stratification according to age as well as its changes during the period of 13 years. 11,273 patients with primary breast cancer from several towns in Croatia were included in this study. Patients' tumour specimens were collected from 1990 to 2002 and were analysed on estrogen (ER) and progesterone (PR) receptors in the Laboratory of the Department of Medical Oncology, University Hospital Centre Zagreb. More than half of our breast cancer patients had ER positive tumours (54.3%). We observed ER + tumours increased with age continuously, with highest percentage in the age group of 70 to 79 years (68.1%). Similarly, proportion of PR + tumours was higher in the older age groups, being the highest between 40 and 49 years (55.9%). During 13 years of the study, the increase in frequency and proportion of ER + tumours was observed (from 52% in 1990 to 62% in 2002) and decrease of PR + tumours (56% to 53%). We confirm previous findings that the risk of hormone dependent breast cancer increases with aging. Risk of ER + breast cancer increased for 10% from 1990 to 2002 and PR + tumours decreased for 3.5% in the same period.
Abstract (croatian)
Cilj ovog rada je istražiti status hormonskih receptora karcinoma dojke kod naših pacijentica, stratificirati ih prema dobi, te utvrditi mijenja li se status receptora tijekom 13 godina praćenja pacijentica. U istraživanje je bilo uključeno 11 273 pacijentica s primarnim karcinomom dojke, iz nekoliko gradova Hrvatske. Uzorci tumora prikupljani su od 1990. do 2002. godine, te je učinjena analiza statusa estrogenskih i progesteronskih receptora u Laboratoriju Zavoda za patofiziologiju, Kliničkog bolničkog centra Zagreb. Većina pacijentica imala je pozitivne estrogenske receptore u tumoru (54,3%). Uočili smo kontinuirani porast učestalosti estrogen pozitivnih tumora s dobi, s najvišom učestalosti u dobnoj skupini od 70 do 79 godina (68,1%). Slično, udio progesteron pozitivnih tumora raste s dobi, te je najviši između 40 i 49 godina (55,9%). Tijekom 13 godina istraživanja, uočen je porast broja i postotka estrogen pozitivnih tumora (s 52% 1990.g. na 62% 2002.g.) te smanjenje progesteron pozitivnih tumora (s 56% na 53%). Ovim istraživanjem potvrđeni su rezultati ranijih studija kojima je utvrđen porast hormon ovisnih tumora s dobi. Rizik estrogen pozitivnih karcinoma dojke porastao je od 1990.g. do 2002.g. za 10%, dok se rizik progesteron pozitivnih smanjio za 3,5%.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 31, no. 2, pp. 535-540
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:956718
Publication2007-06
Document URLhttps://hrcak.srce.hr/27411
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:55:11