prikaz prve stranice dokumenta Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002
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Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002
Collegium Antropologicum, 31 (2007), 2; 535-540. urn:nbn:hr:105:956718
Vrbanec, Damir; Petričević, Branka

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Vrbanec, D. i Petričević, B. (2007). Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002. Collegium Antropologicum, 31. (2), 535-540. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:105:956718

Vrbanec, Damir i Branka Petričević. "Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002." Collegium Antropologicum, vol. 31, br. 2, 2007, str. 535-540. https://urn.nsk.hr/urn:nbn:hr:105:956718

Vrbanec, Damir i Branka Petričević. "Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002." Collegium Antropologicum 31, br. 2 (2007): 535-540. https://urn.nsk.hr/urn:nbn:hr:105:956718

Vrbanec, D. i Petričević, B. (2007) 'Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002', Collegium Antropologicum, 31(2), str. 535-540. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:105:956718 (Datum pristupa: 13.05.2024.)

Vrbanec D, Petričević B. Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002. Collegium Antropologicum [Internet]. 06.2007. [pristupljeno 13.05.2024.];31(2):535-540. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:956718

D. Vrbanec i B. Petričević, "Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002", Collegium Antropologicum, vol. 31, br. 2, str. 535-540, Lipanj 2007. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:956718. [Citirano: 13.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:956718
Podaci o radu
Naslov (engleski)Estrogen and progesterone receptor status in primary breast cancer: a study of 11,273 patients from the year 1990 to 2002
AutorDamir Vrbanec
AutorBranka Petričević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The aim of this study was to gain insight of the breast cancer hormone receptor status of our patients, its stratification according to age as well as its changes during the period of 13 years. 11,273 patients with primary breast cancer from several towns in Croatia were included in this study. Patients' tumour specimens were collected from 1990 to 2002 and were analysed on estrogen (ER) and progesterone (PR) receptors in the Laboratory of the Department of Medical Oncology, University Hospital Centre Zagreb. More than half of our breast cancer patients had ER positive tumours (54.3%). We observed ER + tumours increased with age continuously, with highest percentage in the age group of 70 to 79 years (68.1%). Similarly, proportion of PR + tumours was higher in the older age groups, being the highest between 40 and 49 years (55.9%). During 13 years of the study, the increase in frequency and proportion of ER + tumours was observed (from 52% in 1990 to 62% in 2002) and decrease of PR + tumours (56% to 53%). We confirm previous findings that the risk of hormone dependent breast cancer increases with aging. Risk of ER + breast cancer increased for 10% from 1990 to 2002 and PR + tumours decreased for 3.5% in the same period.
Sažetak (hrvatski)
Cilj ovog rada je istražiti status hormonskih receptora karcinoma dojke kod naših pacijentica, stratificirati ih prema dobi, te utvrditi mijenja li se status receptora tijekom 13 godina praćenja pacijentica. U istraživanje je bilo uključeno 11 273 pacijentica s primarnim karcinomom dojke, iz nekoliko gradova Hrvatske. Uzorci tumora prikupljani su od 1990. do 2002. godine, te je učinjena analiza statusa estrogenskih i progesteronskih receptora u Laboratoriju Zavoda za patofiziologiju, Kliničkog bolničkog centra Zagreb. Većina pacijentica imala je pozitivne estrogenske receptore u tumoru (54,3%). Uočili smo kontinuirani porast učestalosti estrogen pozitivnih tumora s dobi, s najvišom učestalosti u dobnoj skupini od 70 do 79 godina (68,1%). Slično, udio progesteron pozitivnih tumora raste s dobi, te je najviši između 40 i 49 godina (55,9%). Tijekom 13 godina istraživanja, uočen je porast broja i postotka estrogen pozitivnih tumora (s 52% 1990.g. na 62% 2002.g.) te smanjenje progesteron pozitivnih tumora (s 56% na 53%). Ovim istraživanjem potvrđeni su rezultati ranijih studija kojima je utvrđen porast hormon ovisnih tumora s dobi. Rizik estrogen pozitivnih karcinoma dojke porastao je od 1990.g. do 2002.g. za 10%, dok se rizik progesteron pozitivnih smanjio za 3,5%.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium Antropologicum
Brojčani podacivol. 31, br. 2, str. 535-540
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:956718
Datum objave publikacije2007-06
URL dokumentahttps://hrcak.srce.hr/27411
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:55:11