prikaz prve stranice dokumenta Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima
Access restricted to students and staff of home institution
undergraduate thesis
Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2018. urn:nbn:hr:159:222196
Marin, Petra
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Cell Technology, Application and Biotransformations

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Marin, P. (2018). Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:222196

Marin, Petra. "Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2018. https://urn.nsk.hr/urn:nbn:hr:159:222196

Marin, Petra. "Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2018. https://urn.nsk.hr/urn:nbn:hr:159:222196

Marin, P. (2018). 'Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 30 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:222196

Marin P. Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2018 [cited 2024 November 30] Available at: https://urn.nsk.hr/urn:nbn:hr:159:222196

P. Marin, "Enantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:159:222196

Metadata
TitleEnantioselektivna redukcija prokiralnih ketona pomoću kvasca Saccharomyces cerevisiae u prirodnim eutektičkim otapalima
Title (english)Enantioselective reduction of prochiral ketones with YEAST Saccharomyces cerevisiae in natural deep eutectic solvents
AuthorPetra Marin
MentorMarina Cvjetko Bubalo (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
(Laboratory for Cell Technology, Application and Biotransformations)
Zagreb
Defense date and country2018-07-09, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Primjenom pristupa zelene kemije u proizvodnji biološki aktivnih spojeva nastoji se smanjiti negativan učinak klasične kemijske sinteze na okoliš te zamijeniti hlapljiva organska otapala s alternativnim zelenim otapalima. U ovom radu ispitana je mogućnost primjene kvasca Saccharomyces cerevisiae kao biokatalizatora za enantioselektivnu redukciju 1-(3,4-dimetilfenil)etanona i 1-(2,4,6-trimetilfenil)etanona u prirodnim eutektičkim otapalima (NADES) na bazi kolin-klorida. NADES su se pokazala kao povoljan odabir za ispitivane redukcije obzirom na postignuto iskorištenje reakcije te enantiomerni suvišak. Na temelju dobivenih rezultata, zaključuje se da se vrijednosti ispitanih parametara povećavaju povećanjem udjela vode te uporabom supstrata s manjim brojem supstituenata čiji ortho- položaj na fenolnom prstenu nepovoljno utječe na redukciju.
Abstract (english)
Within the concept of green chemistry in the production of biologically active compounds, the negative effect of classical chemical synthesis on environment should be reduced and volatile organic solvents replaced with alternative green solvents. In this study, the application of Saccharomyces cerevisiae yeast as a biocatalyst for enantioselective reduction of 1-(3,4-dimethylphenyl)ethanone and 1-(2,4,6-trimethylphenyl)ethanone in choline chloride-based natural eutectic solvents (NADES) was performed. NADES have been shown to be a preferred choice for the investigated reductions due to the achieved reaction yield and enantiomeric excess. Based on results, it is concluded that the values of the examined parameters are increased by increasing the water content in NADES and using the substrate with a lower number of substituents whose ortho- position on the phenolic ring adversely affects the reduction.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:222196
Study programmeTitle: Biotechnology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2019-09-13 11:47:29