prikaz prve stranice dokumenta Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode
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master's thesis
Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2018. urn:nbn:hr:159:629573
Buljan, Petra
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Food Quality Control
Laboratory for Food Quality Control

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Buljan, P. (2018). Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:629573

Buljan, Petra. "Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2018. https://urn.nsk.hr/urn:nbn:hr:159:629573

Buljan, Petra. "Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2018. https://urn.nsk.hr/urn:nbn:hr:159:629573

Buljan, P. (2018). 'Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 23 December 2024, https://urn.nsk.hr/urn:nbn:hr:159:629573

Buljan P. Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2018 [cited 2024 December 23] Available at: https://urn.nsk.hr/urn:nbn:hr:159:629573

P. Buljan, "Validacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:159:629573

Metadata
TitleValidacijski postupci u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode
Title (english)Validation procedures while determining Streptomycin and Dihydrostreptomycin residues in honey using UHPLC-MS/MS method
AuthorPetra Buljan
MentorMirjana Hruškar (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Food Quality Control)
(Laboratory for Food Quality Control)
Zagreb
Defense date and country2018-07-18, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Rast prisutnosti antibiotske rezistencije u 21. stoljeću zahtijeva strože analitičke kontrole prehrambenih proizvoda, a samim time i razvoj novih analitičkih metoda. Cilj ovog istraživanja bio je odrediti validacijske postupke u određivanju streptomicina i dihidrostreptomicina u medu primjenom UHPLC-MS/MS metode. Određivani validacijski parametri bili su: specifičnost, linearnost, ponovljivost, unutarlaboratorijska reproducibilnost, preciznost, mjerna nesigurnost, granične koncentracije i robusnost. Metoda se pokazala brzom, jednostavnom, te su rezultati validacije zadovoljili sve kriterije zakonskog okvira donesenog uredbom Europske komisije 657/2002. S obzirom na dobivene rezultate, metoda je prikladna za određivanje streptomicina i dihidrostreptomicina u medu.
Abstract (english)
Increase of antibiotic resistance in the 21st century demands more severe analytical control of food products, and hence the development of new analytical methods. The aim of this study was to determine validation procedures for the determination of streptomycin and dihydrostreptomycin in honey using the UHPLC-MS/MS method. Determined validation parameters were: specificity, linearity, repeatability, intra-laboratory reproducibility, precision, measurement uncertainty, limit of detection and quantification, and robustness. The method had proven to be quick and simple, and the results of the validation met all the criteria given by the European Commission Regulation 657/2002. Considering the acquired data, this method is suitable for the determination of streptomycin and dihydrostreptomycin in honey.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:629573
Study programmeTitle: Food Safety Management
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka upravljanja sigurnošću hrane (magistar/magistra inženjer/inženjerka upravljanja sigurnošću hrane)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-11-26 13:36:28