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doctoral thesis
Utjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. urn:nbn:hr:159:371514
Magaš, Saša
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Food Quality Control
Laboratory for Nutrition Science

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Magaš, S. (2020). Utjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2 (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:371514

Magaš, Saša. "Utjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:371514

Magaš, Saša. "Utjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:371514

Magaš, S. (2020). 'Utjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2', Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 30 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:371514

Magaš S. Utjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2 [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2020 [cited 2024 November 30] Available at: https://urn.nsk.hr/urn:nbn:hr:159:371514

S. Magaš, "Utjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2", Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:159:371514

Metadata
TitleUtjecaj prehrambenoga portfelja (prehrambena vlakna, ginseng i Salvia hispanica L.) na lipidogram oboljelih od šećerne bolesti tipa 2
Title (english)The effectiveness of the food portfolio (dietary fiber blend, ginseng and Salvia hispanica L.) on lipidogram in type 2 diabetic patients
AuthorSaša Magaš
MentorZvonimir Šatalić (mentor)
MentorLea Smirčić-Duvnjak (komentor)
Committee memberInes Panjkota-Krbavčić (predsjednik povjerenstva)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Food Quality Control)
(Laboratory for Nutrition Science)
Zagreb
Defense date and country2020-07-02, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Nutrition
Universal decimal classification
(UDC)		616 - Pathology. Clinical medicine
Abstract
Cilj ovog rada bio je ispitati mogući komplementarni učinak američkog i korejskog crvenog ginsenga, mješavine viskoznih vlakana i sjemenki chie-Salviae hispanice, kao sastavnica prehrambenoga portfelja, na lipidogram oboljelih od šećerne bolesti tipa 2. Ova dvostruko slijepa randomizirana, placebom kontrolirana studija, trajanja 24 tjedna, napravljena je u 2 istraživačka centra na 104 sudionika oboljela od šećerne bolesti tipa 2. Nakon 24 tjedna u testnoj skupini postignuto je statistički značajno smanjenje koncentracije glikiranog hemoglobina (HbA1c) od -0,27  0,13 %. Nije zabilježen statistički značajan učinak ispitivanog prehrambenoga portfelja niti na jednu frakciju lipidograma oboljelih od šećerne bolesti tipa 2. Nije pronađena statistički značajna razlika niti u omjeru ukupnog i HDL kolesterola. Nije postignut statistički značajan učinak ispitivanog prehrambenoga portfelja na razinu visoko osjetljivog C-reaktivnog proteina (hs CRP). Pokazano je da uzimanje četverodijelnoga portfelja i uz standardnu farmakološku terapiju ima dodatni povoljan učinak na regulaciju glikemije (smanjenje HbA1c) u oboljelih od šećerne bolesti tipa 2. Nema utjecaja ispitivanog prehrambenoga portfelja na profil lipida u plazmi u oboljelih od šećerne bolesti tipa 2 liječenih standardnim lijekovima.Ovaj prehrambeni portfelj mogao bi se koristiti kao dodatna terapija u pokušaju regulacije glikemije, a u svrhu ispitivanja učinkovitosti na lipidogram oboljelih od šećerne bolesti tipa 2 potrebna su daljnja istraživanja.
Abstract (english)
The aim of this thesis was to examine the possible complementary effect of American and Korean red ginseng, a mixture of viscous fibers and chia-Salvia hispanica seeds, as nutritional portfolio components, on lipidogram of patients with type 2 diabetes. This double-blind, randomized, placebo-controlled, 24-week study was conducted in 2 research centers on 104 participants with type 2 diabetes. After 24 weeks, a statistically significant additional HbA1c decrease of -0.27 ± 0.13% was achieved in the test group. No statistically significant effect of the tested dietary portfolio was observed on any lipid fraction in patients with type 2 diabetes mellitus. No statistically significant difference was found in the ratio of total to HDL cholesterol. No statistically significant effect of the tested food portfolio on the level of highly sensitive C-reactive protein (hs CRP) was achieved. It has been shown that taking a four-part portfolio along with standard pharmacological therapy has an additional beneficial effect on glycemic control (lowering HbA1c) in patients with type 2 diabetes. There was no influence of the tested nutritional portfolio on the plasma lipid profile in type 2 diabetic patients treated with standard hypolipemic drugs. In an attempt to regulate glycemia, this nutritional portfolio could be used as additional therapy. Further studies are needed to test the efficacy of the nutritional portfolio on lipidogram in type 2 diabetic patients.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:371514
Promotion2020-07-02
Study programmeTitle: Postgraduate PhD Study in Nutrition
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje biotehničkih znanosti, polje nutricionizam (doktor/doktorica znanosti, područje biotehničkih znanosti, polje nutricionizam)
Type of resourceText
Extent98 str. ; 30 cm
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2020-07-02 09:36:52