prikaz prve stranice dokumenta Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L.
Embargo period 2026-03-27
master's thesis
Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L.
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. urn:nbn:hr:163:897178
Petrović, Iva
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacognosy

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Petrović, I. (2024). Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L. (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:897178

Petrović, Iva. "Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L.." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:897178

Petrović, Iva. "Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L.." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:897178

Petrović, I. (2024). 'Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L.', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:897178

Petrović I. Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L. [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2024 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:163:897178

I. Petrović, "Optimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L.", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:163:897178

Metadata
TitleOptimizacija ultrazvučne ekstrakcije polifenolnih spojeva iz vrste Satureja montana L.
Title (english)Optimisation of ultrasound extraction of polyphenols from species Satureja montana L.
AuthorIva Petrović
MentorMarijana Zovko Končić (mentor)
Committee memberMarijana Zovko Končić (predsjednik povjerenstva)
Committee memberMaja Bival Štefan (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacognosy)
Zagreb
Defense date and country2024-03-27, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
S. montana L. aromatična je biljaka bogata bioaktivnim fenolnim spojevima. U ovom istraživanju spektrofotometrijski je ispitivan sadržaj ukupnih polifenolnih spojeva, fenolnih kiselina i flavonoida te sadržaj luteolin-7-O-glikozida upotrebom HPLC-a. Korištena je ekološki prihvatljiva metoda ultrazvučne ekstrakcije te su primjenjivani različiti ekstrakcijski uvjeti. Cilj je bio pronaći uvjete koji daju najučinkovitiju ekstrakciju s najvećim prinosom fenolnih spojeva. Pokazana je efikasnost prisustva HP-β-CD, kao sredstva koje omogućuje inkapsulaciju polifenola, te kombinacije glicerola i vode kao otapala. Najveći prinos ukupnih polifenola i fenolnih kiselina dao je pripravak s uvjetima 70 % GL, 0,2 mmol HP-β-CD, pri 45 °C, 25 min i USP od 432 W. Ekstrakciji flavonoida najviše su pogodovali uvjeti 35 % GL, 0,2 mmol HP-β-CD, 15 min na 70 °C s USP od 720 W, a LG uvjeti 35 % GL, 0,2 mmol HP-β-CD, 20 °C, 15 min s USP od 720 W.
Abstract (english)
S. montana L. is an aromatic species rich in bioactive phenolics. In this work, spectrophotometric analysis of total polyphenols, phenolic acids and flavonoids in the extract was conducted, as well as content quantification of luteolin-7-O-glicoside using HPLC. Environmentally friendly ultrasound extraction method was used, and different extraction conditions were applied. The purpose was to find conditions giving the most effective yield of measured substances. The results have shown the efficiency of having HP-β-CD present, as an encapsulating agent, as well as glycerol – water mixture as a solvent. The biggest yield of total polyphenols and phenolic acids was shown in extraction conditions of 70 % GL, 0,2 mmol HP-β-CD, 45 °C, 25 min and USP of 432 W. To the flavonoid extraction favoured the most conditions of 35 % GL, 0,2 mmol HP-β-CD, 15 min on 70 °C with USP of 720 W, and for LG conditions of 35 % GL, 0,2 mmol HP-β-CD, 20 °C, 15 min and USP of 720 W.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:897178
Study programmeTitle: Pharmacy - integrated undergraduate and graduate - university study
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
Type of resourceText
File originBorn digital
Access conditionsEmbargoed access
Embargo expiration date: 2026-03-27
Terms of useLicence In copyright icon
Created on2024-05-23 14:32:24