prikaz prve stranice dokumenta Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3
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Scientific paper - Conference paper
Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3
Croatian Medical Journal, 65 (2024); 209. urn:nbn:hr:217:903234
Glunčić, Matko; Vlahović, Ines; Rosandić, Marija; Paar, Vladimir

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Glunčić, M., Vlahović, I., Rosandić, M. & Paar, V. (2024). Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3. Croatian Medical Journal, 65.. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:903234

Glunčić, Matko, et al. "Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3." Croatian Medical Journal, vol. 65, 2024. https://urn.nsk.hr/urn:nbn:hr:217:903234

Glunčić, Matko, Ines Vlahović, Marija Rosandić and Vladimir Paar. "Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3." Croatian Medical Journal 65 (2024). https://urn.nsk.hr/urn:nbn:hr:217:903234

Glunčić, M., et al. (2024) 'Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3', Croatian Medical Journal, 65. Available at: https://urn.nsk.hr/urn:nbn:hr:217:903234 (Accessed 03 October 2024)

Glunčić M, Vlahović I, Rosandić M, Paar V. Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3. Croatian Medical Journal [Internet]. 2024 [cited 2024 October 03];65. Available at: https://urn.nsk.hr/urn:nbn:hr:217:903234

M. Glunčić, I. Vlahović, M. Rosandić and V. Paar, "Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3", Croatian Medical Journal, vol. 65, 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:217:903234. [Accessed: 03 October 2024]

Metadata
Title (english)Precise identification of cascading alpha satellite higher order repeats in T2TCHM13 assembly of human chromosome 3
AuthorMatko Glunčić
AuthorInes Vlahović
AuthorMarija Rosandić
AuthorVladimir Paar
Author's institutionUniversity of Zagreb
Faculty of Science
(Department of Physics)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Abstract (english)
Aim. To precisely identify and analyze alpha-satellite higher-order repeats (HORs) in T2T-CHM13 assembly of human chromosome 3. Methods. From the recently sequenced complete T2TCHM13 assembly of human chromosome 3, the precise alpha satellite HOR structure was computed by using the novel high-precision GRM2023 algorithm with global repeat map (GRM) and monomer distance (MD) diagrams. Results. The major alpha satellite HOR array in chromosome 3 revealed a novel cascading HOR, housing 17mer HOR copies with subfragments of periods 15 and 2. Within each row in the cascading HOR, the monomers were of different types, but different rows within the same cascading 17mer HOR contained more than one monomer of the same type. Each canonical 17mer HOR copy comprised 17 monomers belonging to 16 different monomer types. Another pronounced 10mer HOR array was of the regular Willard’s type. Conclusion. Our findings emphasize the complexity within the chromosome 3 centromere as well as deviations from expected highly regular patterns.
Keywords (english)
Languageenglish
Publication typeScientific paper - Conference paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 65, 209
p-ISSN0353-9504
e-ISSN1332-8166
URN:NBNurn:nbn:hr:217:903234
Publication2024
ProjectNumber: KK.01.1.1.01.0004
Title (croatian): Provedba vrhunskih istraživanja u sklopu Znanstvenog centra izvrsnosti za kvantne i kompleksne sustave te reprezentacije Liejevih algebri
Title (english): Implementation of top research within the Scientific Center of Excellence for Quantum and Complex Systems, and Representations of Lie Algebras
Acronym: QuantiXLie
Leader: Hrvoje Buljan
Jurisdiction: eu
Funding stream: European Regional Development Fund
ProjectNumber: IP-2019-04-2757
Title (croatian): Varijante u repetitivnim strukturama višeg reda u centromernim i NBPF dijelovima genoma čovjeka i viših primata
Title (english): Variants in higher order repeat structures in centromeric and NBPF regions of human and higher primates genomes
Acronym: HORVAR
Leader: Matko Glunčić
Jurisdiction: Croatia
Funding stream: Research Projects
ConferenceTitle: 13th International Society for Applied Biological Sciences
Acronym: ISABS
Location: Split, Croatia
Start date: 2024-06-17
End date: 2024-06-22
Document URLhttp://www.cmj.hr/2024/65/3/38868967.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Public noteReceived: April 10, 2024. Accepted: May 28, 2024.
Created on2024-07-23 20:53:57