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undergraduate thesis
Kemija kanabinoida
Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2024. urn:nbn:hr:109:014453
Petek, Lara
Josip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
Department of Applied Chemistry and Ecology
Sub-department of Chemistry and Ecology

Institutional repository: Repository of the Faculty of Food Technology Osijek

Cite this document

Petek, L. (2024). Kemija kanabinoida (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY. Retrieved from https://urn.nsk.hr/urn:nbn:hr:109:014453

Petek, Lara. "Kemija kanabinoida." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2024. https://urn.nsk.hr/urn:nbn:hr:109:014453

Petek, Lara. "Kemija kanabinoida." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2024. https://urn.nsk.hr/urn:nbn:hr:109:014453

Petek, L. (2024). 'Kemija kanabinoida', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, accessed 26 December 2024, https://urn.nsk.hr/urn:nbn:hr:109:014453

Petek L. Kemija kanabinoida [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY; 2024 [cited 2024 December 26] Available at: https://urn.nsk.hr/urn:nbn:hr:109:014453

L. Petek, "Kemija kanabinoida", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, Osijek, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:109:014453

Metadata
TitleKemija kanabinoida
Title (english)Chemistry of Cannabinoids
AuthorLara Petek
MentorValentina Bušić (mentor)
GranterJosip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
(Department of Applied Chemistry and Ecology)
(Sub-department of Chemistry and Ecology)
Osijek
Defense date and country2024-09-02, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Cannabis sativa je biljka koja je poznata još iz rane povijesti u različitim kulturama. Biljka sadrži biološki aktivne sastojke, a to su kanabinoidi. Kanabinoidi se dijele na fitokanabinoide, endokanabinoide te sintetske kanabinoide. Najpoznatiji kanabinoid je tetrahidrokanabinol (THC) koji ima psihoaktivne učinke, a drugi najpoznatiji je kanabidiol (CBD) koji nema psihoaktivne učinke i koristi se u terapijske svrhe. Kanabinoidi se danas koriste u medicinske svrhe za ublažavanje boli, liječenje epilepsije te kod poboljšanja mentalnog zdravlja. Ekstrakcijom kanabinoida dobivaju se čisti i učinkoviti proizvodi. Bioraspoloživost kanabinoida ovisi o načinu njihove primjene. Prvi sintetski kanabinoidi otkriveni su u Spice-u i nazvani su prema profesoru organske kemije Johnu W. Huffmanu. Glavne metaboličke reakcije koje su vezane uz sintetske kanabinoide su oksidacija aromatskih i alkilnih struktura. Sintetski kanabinoidi većinom se izlučuju u bubrezima nakon metaboličke transformacije. Danas toksičnost sintetskih spojeva nije u potpunosti razjašnjena, ali se vjeruje kako neki metaboliti koji imaju naftilnu jedinicu mogu posjedovati kancerogeno djelovanje. Spojevi koji potpuno djeluju kao agonisti na CB1 receptoru u prekomjernoj konzumaciji mogu izazvati po život opasne intoksikacije. Hipertenzija i tahikardija su jedne od posljedica konzumacije sintetskih kanabinoida. Tijekom konzumacije sintetskih kanabinoida može doći i do pojave mučnina koje mogu uzrokovati povraćanje. Kserostomija, topla/suha koža, hiperglikemija, bljedilo ili crvenilo kože su samo neki od štetnih učinaka nakon konzumacije sintetskih kanabinoida. Podaci o farmakodinamici i farmakokinetici sintetskih kanabinoida su ograničeni. Potrošači su uvjerenja kako su sintetski kanabinodi sigurni za konzumaciju te kako nemaju nikakvih posljedica na ljudsko zdravlje.
Abstract (english)
Cannabis sativa is a plant that has been known since early history in different cultures. The plant contains biologically active ingredients, namely cannabinoids. Cannabinoids are divided into phytocannabinoids, endocannabinoids and synthetic cannabinoids. The best-known cannabinoid is tetrahydrocannabinol (THC), which has psychoactive effects, and the second best-known is cannabidiol (CBD), which has no psychoactive effects and is used for therapeutic purposes. Today, cannabinoids are used for medical purposes to relieve pain, treat epilepsy and improve mental health. By extracting cannabinoids, pure and effective products are obtained. The bioavailability of cannabinoids depends on the way they are administered. The first synthetic cannabinoids discovered were discovered in Spice and named after professor of Organic Chemistry John W. Huffman (JWH). The main metabolic reactions associated with synthetic cannabinoids are the oxidation of aromatic and alkyl structures. Synthetic cannabinoids are mostly excreted in the kidneys after metabolic transformation. Today, the toxicity of synthetic compounds is not fully elucidated, but it is believed that some metabolites that have a naphthyl unit may have carcinogenic effects. Hypertension and tachycardia are one of the consequences of consuming synthetic cannabinoids. During the consumption of synthetic cannabinoids, nausea can also occur, which can cause vomiting. Xerostomia, warm/dry skin, hyperglycemia, pallor or redness of the skin are just some of the adverse effects after consuming synthetic cannabinoids. Data on the pharmacodynamics and pharmacokinetics of synthetic cannabinoids are limited. Therefore, consumers are convinced that synthetic cannabinoids are safe for consumption and that there are no consequences for human health.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:109:014453
Study programmeTitle: Food Technology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2024-09-11 13:15:25