prikaz prve stranice dokumenta Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk
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Scientific paper - Original scientific paper
Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk
Anticancer Research, 39 (2019), 8; 4285-4289. https://doi.org/10.21873/anticanres.13593
Tomasovic-Loncaric, Cedna; Fucic, Aleksandra; Andabak, Ana; Andabak, Matej; Ceppi, Marcello; Bruzzone, Marco; Vrdoljak, Danko; Vucicevic-Boras, Vanja

Institutional repository: University of Zagreb School of Dental Medicine Repository

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Tomasovic Loncaric, C., Fucic, A., Andabak, A., Andabak, M., Ceppi, M., Bruzzone, M. ... Vucicevic Boras, V. (2019). Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk. Anticancer Research, 39. (8), 4285-4289. doi: 10.21873/anticanres.13593

Tomasovic Loncaric, Cedna, et al. "Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk." Anticancer Research, vol. 39, no. 8, 2019, pp. 4285-4289. https://doi.org/10.21873/anticanres.13593

Tomasovic Loncaric, Cedna, Aleksandra Fucic, Ana Andabak, Matej Andabak, Marcello Ceppi, Marco Bruzzone, Danko Vrdoljak and Vanja Vucicevic Boras. "Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk." Anticancer Research 39, no. 8 (2019): 4285-4289. https://doi.org/10.21873/anticanres.13593

Tomasovic Loncaric, C., et al. (2019) 'Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk', Anticancer Research, 39(8), pp. 4285-4289. doi: 10.21873/anticanres.13593

Tomasovic Loncaric C, Fucic A, Andabak A, Andabak M, Ceppi M, Bruzzone M, and sur.. Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk. Anticancer Research [Internet]. 2019 July 31 [cited 2024 December 26];39(8):4285-4289. doi: 10.21873/anticanres.13593

C. Tomasovic Loncaric, et al., "Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk", Anticancer Research, vol. 39, no. 8, pp. 4285-4289, July 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:127:911572. [Accessed: 26 December 2024]

Metadata
Title (english)Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk
AuthorCedna Tomasovic-Loncaric
AuthorAleksandra Fucic
AuthorAna Andabak
AuthorMatej Andabak
AuthorMarcello Ceppi
AuthorMarco Bruzzone
AuthorDanko Vrdoljak
AuthorVanja Vucicevic-Boras
Author's institution(Dubrava University Hospital)
Author's institutionUniversity of Zagreb
School of Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract (english)
Background/Aim: Oral squamous cell carcinoma (OSCC) is a cancer with poor prognosis due to therapy resistance, locoregional recurrences, and distant metastases. There is on increased interest in profiling the androgen receptor (AR) in cancer biology. The aim of this study was to compare AR and Ki-67 levels in the neoplastic epithelium and stroma between non-metastatic and metastatic stages of OSCC. Patients and Methods: Tissue specimens of 101 non-metastatic and 95 metastatic OSCC patients were analyzed by immunohistochemistry. Results: More than 20% of AR-positive cytoplasmic staining of OSCC epithelium was significantly associated with nuclear AR levels in the epithelium and increased AR levels in the stroma. In metastatic OSCC patients, Ki-67 was significantly higher than in non-metastatic OSCC patients. Conclusion: More than 20% of AR-positive cytoplasmic staining in neoplastic OSSC epithelium is a significant predictor of OSCC progression risk.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAnticancer Research
Numberingvol. 39, no. 8, pp. 4285-4289
p-ISSN0250-7005
e-ISSN1791-7530
DOIhttps://doi.org/10.21873/anticanres.13593
URN:NBNurn:nbn:hr:127:911572
Publication2019-07-31
Document URLhttp://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13593
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-10-24 09:27:03