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Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk
Anticancer Research, 39 (2019), 8; 4285-4289. https://doi.org/10.21873/anticanres.13593
Tomasovic-Loncaric, Cedna; Fucic, Aleksandra; Andabak, Ana; Andabak, Matej; Ceppi, Marcello; Bruzzone, Marco; Vrdoljak, Danko; Vucicevic-Boras, Vanja

Institucijski repozitorij: Repozitorij stomatološkog fakulteta u Zagrebu

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Tomasovic Loncaric, C., Fucic, A., Andabak, A., Andabak, M., Ceppi, M., Bruzzone, M. ... Vucicevic Boras, V. (2019). Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk. Anticancer Research, 39. (8), 4285-4289. doi: 10.21873/anticanres.13593

Tomasovic Loncaric, Cedna, et al. "Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk." Anticancer Research, vol. 39, br. 8, 2019, str. 4285-4289. https://doi.org/10.21873/anticanres.13593

Tomasovic Loncaric, Cedna, Aleksandra Fucic, Ana Andabak, Matej Andabak, Marcello Ceppi, Marco Bruzzone, Danko Vrdoljak i Vanja Vucicevic Boras. "Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk." Anticancer Research 39, br. 8 (2019): 4285-4289. https://doi.org/10.21873/anticanres.13593

Tomasovic Loncaric, C., et al. (2019) 'Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk', Anticancer Research, 39(8), str. 4285-4289. doi: 10.21873/anticanres.13593

Tomasovic Loncaric C, Fucic A, Andabak A, Andabak M, Ceppi M, Bruzzone M, i sur.. Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk. Anticancer Research [Internet]. 31.07.2019. [pristupljeno 26.12.2024.];39(8):4285-4289. doi: 10.21873/anticanres.13593

C. Tomasovic Loncaric, et al., "Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk", Anticancer Research, vol. 39, br. 8, str. 4285-4289, Srpanj 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:127:911572. [Citirano: 26.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:127:911572
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Naslov (engleski)Androgen Receptor as a Biomarker of Oral Squamous Cell Carcinoma Progression Risk
AutorCedna Tomasovic-Loncaric
AutorAleksandra Fucic
AutorAna Andabak
AutorMatej Andabak
AutorMarcello Ceppi
AutorMarco Bruzzone
AutorDanko Vrdoljak
AutorVanja Vucicevic-Boras
Autorova ustanova(Klinička bolnica Dubrava)
Autorova ustanovaSveučilište u Zagrebu
Stomatološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
Background/Aim: Oral squamous cell carcinoma (OSCC) is a cancer with poor prognosis due to therapy resistance, locoregional recurrences, and distant metastases. There is on increased interest in profiling the androgen receptor (AR) in cancer biology. The aim of this study was to compare AR and Ki-67 levels in the neoplastic epithelium and stroma between non-metastatic and metastatic stages of OSCC. Patients and Methods: Tissue specimens of 101 non-metastatic and 95 metastatic OSCC patients were analyzed by immunohistochemistry. Results: More than 20% of AR-positive cytoplasmic staining of OSCC epithelium was significantly associated with nuclear AR levels in the epithelium and increased AR levels in the stroma. In metastatic OSCC patients, Ki-67 was significantly higher than in non-metastatic OSCC patients. Conclusion: More than 20% of AR-positive cytoplasmic staining in neoplastic OSSC epithelium is a significant predictor of OSCC progression risk.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAnticancer Research
Brojčani podacivol. 39, br. 8, str. 4285-4289
p-ISSN0250-7005
e-ISSN1791-7530
DOIhttps://doi.org/10.21873/anticanres.13593
URN:NBNurn:nbn:hr:127:911572
Datum objave publikacije2019-07-31
URL dokumentahttp://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13593
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-10-24 09:27:03