prikaz prve stranice dokumenta Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane
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master's thesis
Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane
Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2012. urn:nbn:hr:109:871721
Đurkan, Ivana
Josip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
Department of Applied Chemistry and Ecology
Sub-department of Biochemistry and Toxicology

Institutional repository: Repository of the Faculty of Food Technology Osijek

Cite this document

Đurkan, I. (2012). Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY. Retrieved from https://urn.nsk.hr/urn:nbn:hr:109:871721

Đurkan, Ivana. "Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane." Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2012. https://urn.nsk.hr/urn:nbn:hr:109:871721

Đurkan, Ivana. "Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane." Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2012. https://urn.nsk.hr/urn:nbn:hr:109:871721

Đurkan, I. (2012). 'Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane', Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, accessed 27 December 2024, https://urn.nsk.hr/urn:nbn:hr:109:871721

Đurkan I. Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY; 2012 [cited 2024 December 27] Available at: https://urn.nsk.hr/urn:nbn:hr:109:871721

I. Đurkan, "Veza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane", Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, Osijek, 2012. Available at: https://urn.nsk.hr/urn:nbn:hr:109:871721

Metadata
TitleVeza porođajne mase i gestacijskih parametara s izloženošću trudnica ohratoksinu A putem hrane
Title (english)Relationship between birth weight and gestational parameters with dietary exposure of pregnant women to ochratoxin A
AuthorIvana Đurkan
MentorTomislav Klapec (mentor)
Committee memberDaniela Čačić Kenjerić (predsjednik povjerenstva)
Committee memberTomislav Klapec (član povjerenstva)
Committee memberIvica Strelec (član povjerenstva)
Committee memberMilena Mandić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
(Department of Applied Chemistry and Ecology)
(Sub-department of Biochemistry and Toxicology)
Osijek
Defense date and country2012-12-07, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Food Safety and Quality
Abstract
Zadatak rada bio je utvrditi povezanost porođajne mase i gestacijskih parametara s izloženošdu ohratoksinu A (OTA) putem hrane. Analizirani su uzorci prvog jutarnjeg urina 40 ispitanica, od kojih je 20 bilo iz ruralne, a 20 iz urbane sredine. OTA i njegov metabolit ohratoksin α (OTα) određeni su HPLC metodom nakon tekućinsko-tekućinske ekstrakcije. Izvršena je i enzimska (β-glukuronidaza i arilsulfataza) hidroliza konjugata. Ispitanice su popunile kratak upitnik o učestalosti konzumacije određenih namirnica (FFQ) kako bi se procijenio unos OTA hranom koji je koreliran s količinom OTA i OTα u urinu. Za razliku od OTA, srednja razina OTα se višestruko povedala nakon enzimskog tretmana. Utvrđen je trend negativne povezanosti, koji nije bio statistički značajan, mase i duljine novorođenčeta i urinarnih koncentracija OTA i OTα. Utvrđen je i nešto vedi dnevni unos OTA ispitanica srednjoškolskog obrazovanja, kao i vede koncentracije OTα u urinu ispitanica srednjoškolskog obrazovanja, te onih najboljeg materijalnog statusa. Sukladno radovima drugih autora, rezultati upućuju na vezu izloženosti i unosa specifičnih namirnica, iako bi detaljno poznavanje izvora namirnica moglo biti presudno u karakterizaciji rizika za fetus.
Abstract (english)
The aim of this work was to determine relationship between birth weight and gestational parameters with dietary exposure to ochratoxin A (OTA). First-void urine samples of 40 subjects, of which 20 was from rural, and 20 from urban area, were analyzed. OTA and its major metabolite ochratoxin α (OTα) were determined by HPLC-FLD following liquid-liquid extraction. Enzymatic hydrolysis (β-glucuronidase/aryl sulfatase) of conjugates was also performed. The subjects filled a short food frequency questionnaire (FFQ) to assess the OTA intake and to correlate it with OTA and OTα urinary concentrations. Unlike OTA, OTα levels increased significantly following enzymatic treatment. A trend of negative correlation was determined, although not statistically significant, between newborn weight and length and urinary OTA and OTα concentrations. Slightly higher daily OTA intake and urinary OTα concentrations were determined in high school educated subjects. Similarly, nonsignificantly higher OTα urinary concentrations were estimated in well-off women. In agreement with other studies, the results indicate a relationship between exposure to OTA and intake of specific foods. Nevertheless, a more detailed knowledge of food sources may be critical in fetal risk characterization.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:109:871721
ProjectNumber: 113-1130473-0334
Title: Sinergističke smjese u antifungalnoj i antimikotoksigenoj zaštiti hrane
Title: Synergistic mixtures in antifungal and antimycotoxigenic food protection
Leader: Tomislav Klapec
Jurisdiction: Croatia
Funder: MZOS
Funding stream: ZP
Study programmeTitle: Food Science and Nutrition
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka nutricionizma i znanosti o hrani (magistar/magistra inženjer/inženjerka nutricionizma i znanosti o hrani)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2015-12-14 11:27:35