Health Insurance is a type of insurance that covers all or a part of the expenses for the treatment of the insured in a way that this risk extends to all insured. In the Republic of Croatia, there is Compulsory Health Insurance prescribed by law and implemented by the Croatian Institute for Health Insurance. Mandatory Health Insurance is financed from various sources, mostly from contributions, the state budget and other sources. The number of insured persons in the Republic of Croatia is around 4.2 million, and the revenues of the Croatian Institute for Health Insurance amounted to around HRK 27 billion at the end of 2020. eHealth is the use of modern information and communication technologies for the needs of the health system (citizens, patients, health workers, etc.). Even before the accession of the Republic of Croatia to the European Union, the Croatian Institute for Health Insurance established cooperation with the health insurance systems of European countries. The aim of this cooperation was to enable their insured persons to use health care services in other countries when necessary. Health Care includes a system of social, group and individual measures, services and activities for the preservation and improvement of health, disease prevention, early detection of disease, timely treatment and health care, rehabilitation and palliative care. Analysts dealing with this issue agree that there are a number of Health Management Challenges to which an appropriate response needs to be found (Ministry of Health and the Croatian Health Insurance Fund). It is a known fact that in this part of the public sector necessary reform measures are needed, which are warned by analysts in the Republic of Croatia, employers' associations, trade unions, political parties and other stakeholders, as well as the EC in its regular reports on the economic situation. The group of "critical" challenges of the health system include: COVID-19, pandemic, health system debts, health system reform and health service waiting lists. The paper attempts to find answers to the stated challenges of the health insurance management.