With drastic increase of incurable diseases, which affects most of the contemporary population, we are witnessing the need for a more intensive presence of hospital pastoral care. Even if the occurrence of severe illness has always followed man and required the presence of empathic care and spiritual strength, this thesis attempts to analyze the understanding and acceptance of that psycho-somatic temptation. It is based on the Bible's understanding of suffering and death in the Old and New Testament, to the contemporary reflection of the Church Pastoral activities. It is implemented on the basis of the "Agreement on hospital care in hospitals and other health facilities and social welfare institutions". From this agreement, special emphasis is placed on the role of the hospital chaplain, followed by the care of sick and bereaved ones, and his dedication to medical personnel in the clinical and medical context, as well as the care of them in nursing homes, in parish communities and hospices. The request for the implementation of the church pastoral care of hospital chaplaincy and it's inevitable important role in assisting nursing in the moments of physical and mental pain of the "homo-patients" is also referred as the imperative of numerous Church documents, with the inescapable spiritual support of sacraments of, the sacrament of patient anointing, of the holy confession and Eucharisty. In the implementation of hospital chaplaincy, it is inescapable role of the prayer and of the deep spirituality, which help individuals to accept this difficult reality, more easily.