In the economy of knowledge, successful jobs are more likely to be those who make the most from employee’s skills, knowledge and creativity at all levels. Yet work design barely exists in vocabulary in many European countries. Work design is the process of defining the way that job will be done and what tasks will be needed for a particular job. Work design determines the tasks that make the job for an individual or a group. Work design is a lost resource in the fight to improve employee competitiveness and well-being, that can also help them effectively use and develop skills in the workplace. Many jobs result in a loss of talent for employees, so work design should be set as a high priority issue for managers and policy makers. Work design refers to determining: who does the job, defining a specific job, the interconnectedness of different elements of the job, the interaction of the prescribed workplace and the role within the wider social physical and organizational context, as well as the task context itself. The main aim of this paper is to present the work design of different occupations, i.e. to analyze the differences, similarities and characteristics of these occupations. According to the case study model, the work design will be described on the example of the professions as bank teller and a computer programmer, work design will be compared by the differences in the job characteristics recognized by Morgeson and Humphrey (2006). The results will also be compared with an objective job description defined by the occupational network.