This paper presents the preliminary results of a small part of a comprehensive study on the factors of independent living of persons with disabilities, conducted within the scientific research project "Platform 50+" (2020-2023) led by the Association of Persons with Disabilities of Croatia (SOIH) and partners Faculty of Education and Rehabilitation and 11 associations of persons with disabilities, members of SOIH. The project coordinator on behalf of the Faculty of Education and Rehabilitation Sciences is full professor Daniela Bratković, PhD. The main goal of the qualitative research included in this paper was to analyze the main assumptions of achieving independent living of adults with disabilities from the perspective of professionals who support them. The research used the principle of intentional sampling, after which a focus group interview was conducted with a group of participants from the Splitsko-Dalmatinska County, professionals with experience in working with people with disabilities in different systems. For the purpose of qualitative analysis of the obtained results, a thematic analysis was applied (Braun and Clarke, 2006) during which four thematic areas were defined: characteristics of everyday life; forms of systematic and professional support and the possibility of choice; access to premises, facilities and services; and self-determination, with associated themes and sub-themes. The results provided insight into the possibilities and obstacles to achieving independent living for people with disabilities from the perspective of professionals in the region as well as recommendations for improvement that can serve in further developing the area of independent living for people with disabilities.