Autistic adults are at increased risk for accompanying health problems and recently there has been an increased rate of suicide attempts in this population. In addition, autistic adults also face many challenges during health examinations. It is necessary to emphasize that this population is not provided with preventive health services. From the earliest days, children with autism experience unpleasant experiences in the hospital environment. According to previous researches, sensory and communication challenges represent the biggest problems in healthcare institutions for both populations. This paper provides an overview of current knowledge in this area around the world and highlights reasonable adjustments that should minimally be applied for more pleasant experiences in healthcare institutions. This research wanted to determine the most common challenges faced by people with autism spectrum disorder during health examinations and to identify the necessary adjustments for them in the health care system. 102 respondents answered the survey questionnaire, after which a quantitative data analysis on a descriptive level was made. The research included parents of children with autism and autistic adults from all over Croatia. The results show the health examinations during which both groups experience the most difficulties, as well as general and sensory difficulties that cause these same unpleasant experiences. Necessary adjustments in the health care system from the experience of parents of children with autism and autistic adults, for which the majority of respondents expressed the highest degree of agreement in the areas of examination organization, structure and predictability, communication and sensory difficulties, were also consolidated. The adaptations serve as a foundation for changes in Croatia aimed at improving the availability of health services for children with autism and autistic adults.