prikaz prve stranice dokumenta Influence of saliva on the results of global laboratory coagulation tests
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Influence of saliva on the results of global laboratory coagulation tests
Australian Dental Journal, 65 (2020), 3; 205-209. https://doi.org/10.1111/adj.12753
Špiljak, B; Šimunović, L; Lapić, I; Rogić, D; Špalj, Stjepan; Vuletić, L

Institucijski repozitorij: Repozitorij Fakulteta dentalne medicine

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Špiljak, B., Šimunović, L., Lapić, I., Rogić, D., Špalj, S. i Vuletić, L. (2020). Influence of saliva on the results of global laboratory coagulation tests. Australian Dental Journal, 65. (3), 205-209. doi: 10.1111/adj.12753

Špiljak, B, et al. "Influence of saliva on the results of global laboratory coagulation tests." Australian Dental Journal, vol. 65, br. 3, 2020, str. 205-209. https://doi.org/10.1111/adj.12753

Špiljak, B, L Šimunović, I Lapić, D Rogić, Stjepan Špalj i L Vuletić. "Influence of saliva on the results of global laboratory coagulation tests." Australian Dental Journal 65, br. 3 (2020): 205-209. https://doi.org/10.1111/adj.12753

Špiljak, B., et al. (2020) 'Influence of saliva on the results of global laboratory coagulation tests', Australian Dental Journal, 65(3), str. 205-209. doi: 10.1111/adj.12753

Špiljak B, Šimunović L, Lapić I, Rogić D, Špalj S, Vuletić L. Influence of saliva on the results of global laboratory coagulation tests. Australian Dental Journal [Internet]. 27.03.2020. [pristupljeno 29.11.2024.];65(3):205-209. doi: 10.1111/adj.12753

B. Špiljak, L. Šimunović, I. Lapić, D. Rogić, S. Špalj i L. Vuletić, "Influence of saliva on the results of global laboratory coagulation tests", Australian Dental Journal, vol. 65, br. 3, str. 205-209, Ožujak 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:271:582482. [Citirano: 29.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:271:582482
Podaci o radu
Naslov (engleski)Influence of saliva on the results of global laboratory coagulation tests
AutorB Špiljak
AutorL Šimunović
AutorI Lapić
AutorD Rogić
AutorStjepan Špalj
AutorL Vuletić
Autorova ustanovaSveučilište u Rijeci
(Fakultet dentalne medicine)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Ortodoncija
Sažetak (engleski)
Background: Oral wounds inevitably come into contact with saliva which can affect the time needed for bleeding to stop. The influence of saliva can be non-specific, related to dilution of blood, and/or mediated by salivary factors that affect haemostasis directly. The aim of this study was to assess if mixing blood with an individual's saliva would affect the rate of its coagulation measured by global coagulation tests, prothrombin time (PT) and activated partial thromboplastin time (APTT). Methods: The study included 30 healthy non-smoking volunteers. Paired blood and unstimulated saliva samples were obtained from each participant and PT and APTT were determined in blood, blood + saliva and blood + water mixtures. Coagulation tests were performed using the mechanical clot detection method. Results: PT was significantly longer in both blood + saliva and blood + water mixtures compared to blood alone. APTT was significantly longer only in blood + water mixture compared to blood. Conclusions: Similarly prolonged PT in both mixtures suggests that both saliva and water prolong coagulation evenly due to their non-specific effect of blood dilution. The finding that APTT was significantly prolonged only when blood was mixed with water could indicate presence of tissue factor in saliva, however, in a concentration too low to influence the results of PT.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAustralian Dental Journal
Brojčani podacivol. 65, br. 3, str. 205-209
p-ISSN0045-0421
e-ISSN1834-7819
DOIhttps://doi.org/10.1111/adj.12753
URN:NBNurn:nbn:hr:271:582482
Datum objave publikacije2020-03-27
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/adj.12753
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2023-01-19 10:28:07