Systematic air quality monitoring at international, state and local levels in the Republic of Croatia is carried out as per its legislation and in line with the Directive on Ambient Air Quality and Cleaner Air for Europe (CAFE). Systematic air quality monitoring, in combination with modelling, is a comprehensive tool for the control, assessment and anticipation of air pollution and research on its effects on human health. The European Union recommends contemporary approaches to the development of advanced information systems that can combine standard methods, procedures and environmental management standards. The main purpose of research was to define an Integrated Information Framework for Real-time Air Quality Monitoring and Assessment. First, a complex hierarchical relationship across legislation, rules and standards, subjects and roles, and air quality monitoring procedures was established in order to define a number of functionalities and an information system architecture. Then, a procedure for developing an information system based on the following service-oriented concepts was defined: automated monitoring process and air quality assessment streams, service-based activities managed by people, information alarms and the possibility of amending business rules. The modelling of a service-oriented architecture was done according to the Service Oriented Modeling and Architecture (SOMA) method and applying the UML diagram. In order to show a multi-layered service-oriented system architecture, the reference IBM SOA architecture instanced with business-aligned services, service components and information model was used. Finally, a prototype for the execution of service-oriented urban air quality monitoring and assessment processes was developed indicating the usability of the proposed methods and models and the efficiency of data from various sources, all with the aim of real-time spatio-temporal reporting using data for the City of Zagreb. For example, real-time air quality monitoring is done through continuous queries over data streams from automated stations and a web-application then uses a web-service to show the map of the City of Zagreb with air quality indices CAQI (Common Air Quality Index) which are adapted for the purpose of informing public on air quality and its impact on health.