The goal of this graduate thesis is to compare the frameworks for cross-platform mobile application development. The observed frameworks are Flutter, Xamarin.Forms, React Native and Jasonette. The comparison is based on popularity, required experience, supported platforms, cost of an application development, performance, programming languages, size of a community contributors, size of the smallest application, utilization of a central processing unit, random access memory usage and energy impact. For the purpose of this paper, two applications were created. The first one is the most basic “Hello World!” application which prints text on the screen for each of the listed frameworks. The purpose of this application is to obtain reference data such as the size of the smallest application that can be made using a particular framework, utilization of the central processing unit, the random-access memory usage and the energy impact. In addition, an application that accesses the camera of the device displays the image on the screen was created. The idea behind this application is to measure utilization of central processing unit, the random-access memory usage and the energy impact for applications that require large amounts of data processing when performing. The frameworks for cross-platform mobile application development allow faster development of application because the source code of the application is written in one program language and the framework translates it to the output as an application that can be run on multiple platforms. The sizes of obtained applications are approximately 50% larger than native applications, the performances depends on the framework and the developer's experience, some software frameworks require the use of development environments for which licenses need to be paid and the possibility of termination of support for the program framework need to be considered.