This thesis is dedicated to investigation of the operational possibilities of LoRa and LoRaWAN technologies, with the aim of analysis of the influence of LoRa communication parameters on the quality of signal transmission in indoor environment. An analysis of the influence of communication parameters such as the spreading factor, the transmit power, the length of the data transmission and the period of data transmission on parameters that indicate the quality of signal transmission, such as the signal to noise ratio (SNR) and the receiving signal strength indicator (RSSI) was carried out. For this purpose, a system for performing the performance analysis of LoRa network communication parameters was developed. The technologies necessary for the development of the system composed of the tool for connecting different services Node-RED, the time series database InfluxDB and the tool for monitoring data visualisation Grafana are described, including the way in which they were implemented. The developed system was used to conduct experiments on the test LoRa network, which lasted from June 24, 2021 to July 23, 2021 on the premises of the Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture (FESB) located in Split, Croatia. The test LoRa network integrated in the developed system consisted of two LoRa user test endnodes and four LoRa gateways, which have been allocated in faculty building to simulate shortrange indoor signal propagation. Based on practical experiments, it has been noticed that the most influential factor on received signal quality is actually the density and type (material) of interfering obstacles through which the signal must propagate. In the case of data transmission at shorter distances with a low level and/or density of obstacles between user devices and LoRa gateways, the spreading factor did not significantly affect the quality of the signal. However, for the greater distances and the number of the obstacles, the transmissions at maximum spreading factor continuously achieved a better received signal quality. It is also observed that the influence of transmit power level on signal quality is not significant in cases where indoor signal propagation takes place over a longer distance with a high level of interfering obstacles. However, the existence of a certain positive influence of increasing the level of transmit power on the quality of the received signal was observed in cases of low or medium level of interfering obstacles, but even then it was a matter of slight influences on the quality of the received signal. Furthermore, the analysis of the obtained results showed that the size of the transmitted data and the time between successive data transmission do not affect the quality of the received signal. The results of the experimental analysis show that proper adjustment of combination of LoRa communication parameters such as the transmitter power, the spreading factor, the message length and the intensity of sending messages can contribute to improving the operation of the LoRa system in terms of achieving a better signal reception quality for different sizes and types of obstacles that may exist during signal propagation.