The aim of this paper is to examine the relationship between professional interests and relationship satisfaction, in other words, to examine if the expression of particular professional interest according to Holland's model affects relationship satisfaction. Using the Actor-partner interdependence model (APIM), not only was the effect of one’s personal professional interests examined, but also the effect of partner’s professional interests on one’s own. Study included 430 participants, or 215 heterosexual romantic couples between the ages of 19 and 65. As a measure of professional interests the Questionnaire for Self-assessment of Professional Interests was used, and as a measure of relationship satisfaction three measures (Perceived Relationship Quality, Satisfaction Index and Relationship Stability Scale) were used, latter combined into one standardized measure named Total Relationship Satisfaction. The results of the research show a significant actor effect of women’s realistic and enterprising interests, and men’s investigative interests on their own relationship satisfaction, which means that the more prominent realistic and enterprising interests are of women, and the investigative interests of men, their own relationship satisfaction is higher. On the other hand, results point to significant partner effects of men’s artistic, investigative and social interests on women’s relationship satisfaction, which means that the more prominent artistic, investigative and social interests of men are, the higher relationship satisfaction seems for women. Nevertheless, professional interests of women don’t seem to have any predictive value for relationship satisfaction of men.