In his graduate work, the author has elaborated on a less known topic from the past of pharmacology from the territory of Croatia. The title of the paper is “The History of Pharmacology in Croatia: Department of Pharmacology at the School of Medicine University of Zagreb (1918-1963)”. The paper emphasises the foundation, development, and role of the Department of Pharmacology of the School of medicine at the University of Zagreb. Since this theme in historiography has not been thoroughly researched so far, he had a great role in writing this graduate work in the archives. The main essence of this paper is based on the material which was kept in the Archives of the Medical Faculty in Zagreb and the Croatian State Archives. The paper is divided into several sections, with the central position occupied by the following chapters: The Establishment of the Faculty of Medicine and Pharmacology, The Department of Pharmacology (1918-1934), The Crisis Period (1934-1936) and The Department of Pharmacology (1936-1963). The author initially analyzed the position of pharmacology before the institute was founded and its place in the discussions held during the establishment of the School of Medicine. After the establishment of the School of Medicine in Zagreb, the author analysed the development of the Department of Pharmacology through three chapters and a series of subchapters. The central role at the Institute from 1918 to 1963 was played by Miroslav Mikuličić and Ivo Ivančević. Their work significantly influenced all segments of the Department, from organization of work to quality of teaching and scientific development. Therefore, through his graduate work, the author attempted to present all these segments and provide an analysis of all key events, persons or other things that significantly influenced the development of the Department. In addition, the author gave a detailed analysis of the crisis of the Department, which peaked in the period from 1934 to 1936 and almost led to its extinction.