Employed mothers face challenges of multiple roles in a society that still has traditional worldview. Discrepancy between the roles leads to conflict, and disharmony of the demands from work and family domain is called work-family conflict. The purpose of this research was to examine the predictors of two directions of work-family conflict based on a set of sociodemographic characteristics, perceived distribution of family responsibilities, dimensions of perfectionism, number of domains of perfectionism and recovery from work of employed mothers. The research was conducted via an online survey. The participants were 488 mothers, who were employed at their current workplace for a minimum of 6 months and worked minimally 20 hours per week. The results showed that mothers who work more hours per week experience greater work-to-family interference. Furthermore, work-to-family interference was greater for mothers who seek less organization and order, but experience greater discrepancy between perceived standards and actual performance, and who are less psychologically detached and relaxed from work and have less control of their leisure time activities. Greater family-to-work interference experience highly educated employed mothers, who perceive that it is their responsibility to take care of the children, who are less organized, have bigger discrepancy between perceived standards and actual performance and use less relaxation and control, but more skills mastery as work recovery strategies.