The thesis deals with the research of the boundaries of the human body through the phenomena of cyborgization and hybridization of embodiment in interdisciplinary contemporary artistic practices after the nineties of the 20th century. The theoretical framework for reading these practices is largely informed by the posthumanist thoughts of authors such as Donna Haraway, Cary Wolfe, Katherine Hayles and Rosa Braidotti, according to whom the human body is an open system, in constant communication with its immediate environment - natural or artificial, and man is removed from his the central position. Although hybrid entities are not a phenomenon of modern society, the development of science and technology has significantly influenced the research of new forms of embodiment and the limits of the human subject. The appearance of a cybernetic organism (cyborg) implies the extension of the human body by means of technology, motivated by correcting the obsolescence of the human body, enhancing bodily experiences, or creating new forms of technologically mediated bodily abilities. Donna Haraway's extended understanding of the cyborg as an emancipatory strategy, as an entity that subverts not only the dichotomy of nature and technology, but also a number of other dualisms that have shaped the Western tradition, cyborgized bodies are also found in artistic projects that explore forms of new corporeality as sites of interspecies encounters as well as territory which can be transformed by blurring the lines between human and non-human. Finally, the issue of disembodiment, i.e. generating new bodies in digital and virtual space, is taken as a significant concept, exploring artists who created new subjects in the form of avatars and new boundaries of corporeality by utilising technologies such as virtual reality (VR).