The town of Opuzen is located in the south of the Republic of Croatia, near the delta of Neretva River. This master thesis examines the city from the perspective of artistic topography, inspired by a project of the Institute of Art History, which entails an insight into the genesis of the city, specifically geographical, traffic and demographic features, as well as the historical context, in order to present the transformation of Opuzen from its creation to its current state. Discovering the urban morphology reveals its accents: monuments that stand out in the city environment and point to the historical life of the city. In the wider area there are two fortifications, Brštanik and Kula Norinska, whose existence and dominance in the landscape remind that in Opuzen there used to be a fortress called Forte Opus, of which nothing has been preserved today. Therefore, space was opened for the next accent, the main city square, which as an ensemble occupies the largest part of the area of the former fortress. In addition to the change from a military function to a settlement, the second biggest change in the landscape of the city, which in history has been labelled as a swamp, was created by the implementation of regulation and land reclamation. At the time of regulation, perhaps the most noticeable accent in the city's panorama, the Stari most, was created. An insight into the significance of these monuments leads to an understanding of the need for their protection, therefore their current state of preservation or neglect is presented as an appeal for conservation. In the context of the importance of monument protection thesis brings a comment on vandalism towards sculpture of Stjepan Filipović, which during Homeland War resulted in its loss in the surroundings of Opuzen. At the end, proposals are offered for the revival of ambient and monumental values, which are found within two documents of the Council of Europe: The Faro Convention and the Declaration of Santiago de Compostela. Also, in the Miroslav Krleža Lexicographic Institute project, called Atlas of Technical Heritage.