Sensors are devices by which it is possible to establish the existence of a measurable property and use them to determine the quantitative value of the monitored physical quantity. Electrochemical sensors principle is based on the recognition of analytes through the active layer of the sensor material, for example electrochemical sensors transform the effect of electrochemical interaction of analyte - electrode into a useful measurable signal. A review of the development of analytical chemistry shows that within the field of chemical sensors, the field of electrochemical sensors demonstrates the greatest development. That type of sensors has a wide range of applications, including the application in biomedicine. Electrochemical sensors used in biomedicine are special electronic devices that can convert biomedical signals into easily measurable electrical signals. Biomedical sensors are a key component of various medical diagnostic instruments and equipment. The development and research of biosensors is a popular scientific and technological field at the intersection of natural and technical sciences (biology, chemistry, chemical engineering, materials science, electronics and physics) in which a multidisciplinary approach is mandatory. Any progress in this field will have a major impact on the future of disease diagnosis and treatment. The fields of personalized and preventive medicine, diagnostics and drug discovery will have a positive contribution from new sensor technologies.