Recently, waste pharmaceuticals represent an increasing danger for the environment as well as for the human and animal health. The process by which you may get information about the fate, the impact and transport of waste pharmaceuticals in the environment and thus contribute to removing them is called sorption. In this study, the subject of examination was the process of sorption of the pharmaceutically active agent febantel on natural soils and sediments from the Croatian teritory. Febantel is used as a veterinary medicine worldwide. In this study, the mechanism and kinetics of sorption, the impact of ionic strenght and the influence of pH are examined. In order to determine the sorption mechanisms, linear, Freundlich and Dubinin- Radushkevich isotherm model are applied. Experimental data showed the best agreement with the linear model (R^2>0,99), while the rate of sorption is the best described with the kinetic model of pseudo-second-order. The highest values of the coefficient of sorption (Kd) shows a sample of soil Josipovac and sample of sediment Glina, while the lowest values indicate a soil Gračac and sediment Birovača. In the results obtained by examing the influence of ionic strength and pH, there is a noticable trend of increasing sorption coefficient with decreasing ionic strength and pH of the solution.