Since computers have entered into mass usage, there have been efforts to introduce visually impaired into the world of programming. These efforts have been successful and computers have brought a number of advantages for visually impaired, such as easier access to information, books and articles, easier communication, etc. Along with other advantages, computer usage has created new jobs for visually impaired. One of these jobs was programming and software design. Visually impaired programmers have been able to perform their jobs for years since all graphical user interfaces (GUIs) were based on text and developed assistive technology in the form of text to speech converters was sufficient for enabling visually impaired to produce computer code and develop programs. However, the rapid development of GUI in this area, has led the visually impaired programmers to the point where they could no longer cope with the visual aspects of new programming concepts. This transition did not come overnight, but is has soon become clear that existing assistive technology will not be able to cope with all of new graphical concepts. Analyzing current situation, it can be concluded that a visual programming and GUI design are the dominant problems for visually impaired programmers that need an adequate solution. In this doctoral thesis, several different approaches for solution of the problems mentioned are stated along with the discussion about the most effective solution that is proposed as the general solution. Existing efforts in solving the problems mentioned are also stated and described. The research about the need for this kind of solution and about its desired characteristics is also presented. Considering a review of existing efforts to solve this problem a new model is proposed, whose central part consists of a new description language GUIDL (Graphical User Interface Description Language) that enables visually impaired to create visual interfaces in a suitable and simple way using pure textual form. A graphic interface described in GUIDL language is translatable into a form supported by newer software development environments and programming languages in the field of classic desktop programming. In this way proposed solution enables visually impaired to be involved in the design part of the overall software design process.