In this investigation, three samples (Sample 1, Sample 2, Sample 3) of silver-doped titania (TiO2) were prepared by hydrothermal synthesis. Chemicals used for the preparation of this colloidal suspension (sol) were: titanium isopropoxide (precursor), 2-propanol (solvent), acetic acid (catalyst), acetylacetone (complexing agent), sodium borohydride (reduction agent), as well as silver nitrate (source of silver). Prepared nanocrystalized silver-doped titania powders were characterized by means of Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy. Powder X-ray diffraction (PXRD) was used to determine the phase composition and the size of the crystallites. The main goal was to examine the possible application of the synthesized TiO2 as a catalyst for the pharmaceuticals degradation in the advanced oxidation processes in water, under the solar-like radiation. Hydrolytic degradation of nitrofurantoin, an antibiotic used to treat urinary tract infections, by means of heterogeneous photocatalyst with three different nanocrystalline silver-doped TiO2 powders and one commercial TiO2 powder (P25), used for the comparison of the synthesized powders’ photocatalytic properties. Obtained results showed that the hydrolytic degradation of the nitrofurantoin with the solar-like radiation (consists of visible light and UV component) was possible for all three titania samples. The best photocatalytic activity in the nitrofurantoin degradation under the VIS radiation (visible light, without the UV component) was achieved with the Sample 1. Low photocatalytic activity was achieved with the commercial titania sample, while Samples 2 and 3 showed no photocatalytic activity under the VIS radiation.