An organ transplant is a surgical procedure by which one or more organs are taken from a person who donates and transplants to a recipient. Organ transplantation is performed when previously applied treatment methods do not work. Routine techniques can be used to transplant the cornea, cardiovascular tissues, tendons, bones and skin. Skin grafting is a common example of transplantation from one part of a person’s body to another. Different types of organs, tissues, cells and limbs can be transplanted - even the face. In the Republic of Croatia, organ donation is regulated by several laws and the Republic of Croatia is one of the top donors in Europe. Organ donation is the subject of many ethical debates and the reason why many do not decide to do so. The aim of this research is to examine the performance of the existing system by comparing data from the corneal tissue donor database of Clinical Hospital Center Sestre milosrdnice before and after the introduction of the existing tissue collection system. Interrupted time series modeled with seasonal autoregressive integrated moving average were tested to see if a number of variables were assessed to assess the usefulness of implementing a new corneal tissue collection system statistically significantly before and after system implementation. The new system includes the introduction of full-time tissue coordinators. A time period of two years before and after the introduction of the coordinator was observed, and the unit of time was one month. In this study, a high increase in donors was observed in the observed period. In the period after the introduction of full-time tissue coordinators, 45 donors were realized, and after the introduction of coordinators, 205 donors. Of the realized donors, slightly more than half of them are male (146, 58.6%), and this relationship was maintained before (21, 61.4%) and after (119, 58.0%) the introduction of coordinators. On average, after the introduction of the coordinator, 8.3 more donors were realized per month than before the introduction of the coordinator. In the average month after the introduction of the coordinator, there were 3.8 more oral interviews than before the introduction of the coordinator. Data for 2015-2016 years do not follow the same trend as other years, but that later years show similarities in variation. The highest number of deaths occurs consistently in January, and other increases are present in May, August, and October, with the largest declines in deaths in July and September.