It is estimated that in the Republic of Croatia every third person consumes tobacco, which is approximately 30% of the population. Tobacco consumption is present at every age and starts earlier. It is also associated with lower socio-economic status, lower levels of education and lower quality of life. The aim of the study was to examine the incidence of nicotine addiction in health and non-health professionals, to examine the incidence of nicotine addiction with respect to sociodemographic characteristics (gender, education, socioeconomic status), and to examine the quality of life in nicotine addicts. The research was conducted through an anonymous survey among health and non-health professionals of the Republic of Croatia, in period from April 1, 2022 to May 1, 2022. The study included people aged 20 to 65, both sexes. 160 respondents were included in the research. The survey was divided through direct contact with the respondents. The instrumentation consisted of three questionnaires. Socio-demographic data questionnaire made for this research, nicotine consumption questionnaire made for this research and quality of life questionnaire. Contrary to expectations, the research showed that more health workers smoke compared to non-health workers, more respondents with secondary education and higher education consume nicotine compared to the number of non-smokers in the same categories, while the pattern is opposite in higher education, where is a relatively higher number of non-smokers than smokers. It was shown that there is no statistically significant difference in the estimated quality of life between smokers and non-smokers and that there is a significantly higher awareness of the harmfulness of smoking in non-smokers compared to smokers.