Malignant diseases represent a serious global health problem. They can have severe consequences for health and lead to fatal outcomes. Confronting a family with a malignant illness poses a challenging process that can affect all family members. It is characterized by various emotional reactions, changes in family dynamics, and the need to adapt to new roles and responsibilities. The aim of this study is to examine different sources of social support and the level of resilience among families with a member diagnosed with a malignant disease compared to those without a member diagnosed with a malignant disease. There were 60 participants divided into two groups who took part in the study: families with a member diagnosed with a malignant disease and participants without a member diagnosed with a malignant disease. Standardized questionnaires were used, including the Multidimensional Scale of Perceived Social Support and the Family Resilience Assessment Questionnaire. The obtained results indicate that there is no statistically significant difference in perceived social support between the participants coming from families with a member who has a malignant disease and the participants coming from families without such cases. Family support was positively associated with all three types of family resilience, friend support was only associated with Family Connectedness, while support from a significant other was not associated with any type of family resilience. This study emphasizes the importance of the family as a primary source of social support and suggests that different sources of social support can have different effects on various dimensions of family resilience among families caring for individuals with malignant diseases. The findings also highlight the need for support in clinical practice and interventions aimed at supporting families facing malignant diseases.