Aim: The aim of this study is to assess the effectiveness of rehabilitation process of people with lower-limb amputees. Methods and participants: The study included 60 participants with unilateral lower-limb amputation admitted from January to May 2019 to the Institute for Rehabilitation and Orthopaedic Devices of University Hospital Centre Zagreb. The mobility was assessed using the Amputee Mobility predictor without a prosthesis (AMPnoPRO) used for prediction of functional ability of persons by assigning the appropriate K-level. At the completion of the rehabilitation process, the AMPPRO test was used to assess the mobility, while the assessed time spent wearing a prosthesis during the day was expressed in hours per day (h/day) and walking speed was expressed in seconds (s/10 m). The participants have completed Trinity Amputation and Prosthesis Experience Scales Revised-TAPES-R questionnaire, a multidimensional instrument designed to examine the psychosocial processes involved in adjusting to amputation and a prosthesis. Results: The participants with lower amputation level (transtibial amputation, N=33) have shown better functional abilities (P = 0,02) and greater walking speed (P < 0,001), as well as better social adjustment (P = 0,04), significantly better adjustment to limitation (P = 0,005), significantly greater functional satisfaction (P < 0,001) and they have, on average, assessed their activity restriction with lower grade (P = 0,04). A positive correlation between time spent wearing a prosthesis and walking speed (rs > 0,7) as well as better adjustment to limitations (rs= -0,63) and activity restriction (rs=-0,75) have been established. There is a statistically significant correlation between psychosocial adjustment and functional ability parameters (P < 0,001; rs >= 0,6). Conclusion: Age and high level of amputation adversely affect the functional outcomes of rehabilitation, psychosocial adjustment and adjustment to amputation and prosthesis.