Goal of this thesis is to study and compare masonry work technologies. As there are several construction systems, for this comparison we studied three of them: classical masonry and two innovative construction systems. Purpose of this thesis is research of possibilities of construction in innovative systems which are still rarely applied in Croatia, but have the possibility of becoming an unavoidable method of construction in the foreseeable future, especially with family houses and small apartment buildings. Research of materials and elements which are used in these systems has shown benefits and flaws of particular systems. Practical examples for better comparison were made by building the samples of particular systems. Their mutual comparison enables the best and the most optimal system to be found. That system needs to be high-quality in terms of meeting energy requirements, specifically, and satisfaction of conditions for the highest possible value of heat transfer coefficient. Besides, the system needs to be cost-efficient. Costs of particular systems were determined by norms of the materials and work that were collected during the making of practical examples.