Adhesives are non-metal materials that are used to join two or more components based on their chemical and physical properties during the application of adhesive. The adhesion bonding process is possible primarily due to the adhesion and cohesion attraction forces between the adhesive and the adherent. The adhesive binding type, despite its high representation and cost-effectiveness, was for years considered to be a lower quality and less durable option than the sewn binding type. Adhesive binding is growing in popularity due to advancements in adhesive binding technology, shorter delivery time and the introduction of innovative materials. It is suitable for medium volume books (50 – 250 pages) and enables the production of durable and flexible end-products in accordance with today’s market needs. The selection of adhesive type for graphic postprocesses depends on the nature of the adherents, the end-use performance requirements, the production volume and the available adhesive bonding processes. Polyvinyl acetate (PVAc) adhesives are widely used adhesives in the graphic industry for paper, board, leather and cloth. In this study, the modification of PVAc adhesive, suitable for the short runs of graphic products, by adding silica (SiO2) and titanium dioxide (TiO2) nanoparticles was carried out in order to produce more reliable, high-performing adhesive and to increase the end-product quality. The efficacy of PVAc adhesive modification with nanoparticles was systematically investigated. The quality criteria for adhesive bound books are clearly defined by the bookbinding strength, by the peel resistance of adhesive joints and by the definition and assignment of marks for the book opening behaviour and the overall visual impression evaluation. The modification of PVAc adhesive with nanoparticles is successful if the adhesive retains its existing positive properties, such as satisfactory resistance to aging and elasticity and invisibility of the dry adhesive film, with a positive effect of nanoparticles on its limiting properties: end-product strength, long drying time and low resistance to temperature and humidity changes. The optimum nanoparticle concentration in PVAc adhesive was defined by determining the surface free energy and by analysing the morphological structure of the paperadhesive samples by scanning electron microscopy and Fourier transform infrared spectroscopy.The page-pull binding strength results showed a significant increase in binding strength by the addition of 1% SiO2 nanoparticles in PVAc adhesive (10.34% – 27.50%), regardless of the paper type used in a book block. By the addition of 1% TiO2 nanoparticles, the binding strength was slightly decreased or increased (-7.5% – 6.49%), depending on the paper type used for making the book blocks. In addition, the modification of PVAc adhesive caused a significant consistency improvement in binding quality, i.e. a reduction in the coefficient of variation (43.18% – 75.14% [SiO2]; 8.72% – 48.37% [TiO2]). All uncoated book blocks, regardless of the PVAc adhesive type used, achieved very good durability, while the coated book blocks had poor durability and were not suitable for adhesive bookbinding with PVAc adhesives. The modification of PVAc adhesive with SiO2 and TiO2 nanoparticles increased the peel resistance of adhesive joints (6.00% – 23.88% [SiO2]; 2.38% – 9.10% [TiO2]). The addition of SiO2 nanoparticles to the PVAc adhesive had a positive impact on the visual evaluation of the adhesive bookbinding quality. The visual evaluation of the book blocks after adding TiO2 nanoparticles remained almost unchanged or was slightly improved. The elasticity of the adhesive, based on the material toughness, was increased by 9.15% by adding SiO2 nanoparticles. TiO2 nanoparticles significantly reduced the elasticity of PVAc adhesive, by 44.47%. The colour difference between dried PVAc adhesive film and dried nanomodified PVAc adhesive films was not visible, but it was slightly larger for adhesive modified with TiO2 nanoparticles. All adhesives tested showed satisfactory resistance to UV radiation, i.e. accelerated aging. The drying time of nano-TiO2 PVAc adhesive was much shorter than the drying time of unmodified PVAc adhesive. Nano-SiO2 PVAc adhesive had a slightly longer drying time than the original PVAc adhesive. The addition of nanoparticles had a positive effect on increasing the resistance of adhesive joints to temperature and humidity changes. Nano-TiO2 PVAc adhesive joints were the most resistant to these changes. Given that the quality of adhesive joints largely depends on the consistency of the materials, procedures, methods and testing conditions used, it is necessary to define them precisely to (if they are not defined in international standards or is standards do not exist) to ensure the reliability and reproducibility of the results obtained. The guidelines for the systematic investigation of adhesive joint quality are clearly defined in the first data package (PP_01), along with an expected numerical range of the results and the coefficient of variation for each quality test performed, in order to reduce measurement uncertainty and ensure correct evaluation of the results in further research. The second data package (PP_02) provides thequality comparison of all the adhesive joints tested in this study, while the third data package (PP_03) provides a simple quality comparison of all tested groups of adhesive bound books. Based on the results presented, it can be concluded that there is no universal PVAc adhesive that can fulfil all the postpress graphic processes, and it is usually necessary to compromise when selecting the most appropriate adhesive according to a practical adhesive system and the requirements of the end user.