The aim of this study was to determine university students' attitudes and knowledge about palliative care with regard to earlier experience of meeting dying person, loss of someone close, satisfaction with previous palliative education, religious beliefs and field of study. Second aim was to determine whether earlier experience of meeting dying person, loss of someone close, satisfaction with previous palliative education, religious beliefs and field of study were predictors of attitudes and knowledge about palliative care. The survey was conducted on 60 male and 263 female students from different universities in Zagreb and from University of Varaždin. The data were collected through an online questionnaire that was consisted of “Palliative care attitude scale”, “Palliative care knowledge scale”, sociodemographic questions and questions related to previous experience with palliative patients and palliative care. Research findings suggested that students who met a dying person and students who are satisfied with previous palliative education showed greater agreement with statements that indicate positive attitudes toward palliative care. Students whose avocation wasn’t related with palliative care showed negative attitudes toward care of palliative patients. The most significant predictors of attitudes toward palliative care were field of study and satisfaction with previous palliative education. Results of this research also suggested that students who met a dying person, who were satisfied with previous palliative education, medical and nursing students had higher knowledge about palliative care. Significant predictors of knowledge about palliative care were field of study and satisfaction with previous palliative education.