Mouthguards are resistant devices that help prevent injuries during sports activities, in both contact and non-contact sports. Despite their obvious benefit in injury prevention, their use tends to be neglected in most sports, especially during training sessions. There are three main categories of mouthguards - ready-made, semi-adjustable and individual. Each of these types has its specific advantages and disadvantages, but individual mouthguards provide the best retention and comfort. The production of individual mouthguards requires a visit to the dentist which makes this type more expensive than the other two. Due to its significant exposure during sports activities, the orofacial region is the most prone to injuries which can easily be avoided with proper use of mouthguards. There is also certain evidence that mouthguard use can help prevent concussive brain injuries in sports, and that it can enhance performance. Jaw muscle contraction, which happens during mouthguard use, is associated with a simultaneous activation potential mechanism which has a positive effect on sports performance. Furthermore, wearing a ventilated mouthguard has been associated with improved biomechanics of movement and there is evidence of the influence of dental occlusion on body stability during dynamic movements, such as improved balance and accuracy, which is especially significant in sports which require quick reaction time. Ready-made and semi-adjustable mouthguards are affordable and widely available in sporting goods stores, but individually adapted ones, which are made by professionals, are the only ones that provide complete protection and comfort. Due to their importance in injury prevention and their contribution to improving sports performance, better education about mouthguards is required so that their use can become more common in a greater variety of sports, especially during the training process.