prikaz prve stranice dokumenta Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis
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Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis
Gene, 647 (2018); 48-60. https://doi.org/10.1016/j.gene.2018.01.010
Barišić, Anita; Dević Pavlić, Sanja; Ostojić, Saša; Pereza, Nina

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Barišić, A., Dević Pavlić, S., Ostojić, S. i Pereza, N. (2018). Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis. Gene, 647., 48-60. doi: 10.1016/j.gene.2018.01.010

Barišić, Anita, et al. "Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis." Gene, vol. 647, 2018, str. 48-60. https://doi.org/10.1016/j.gene.2018.01.010

Barišić, Anita, Sanja Dević Pavlić, Saša Ostojić i Nina Pereza. "Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis." Gene 647 (2018): 48-60. https://doi.org/10.1016/j.gene.2018.01.010

Barišić, A., et al. (2018) 'Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis', Gene, 647, str. 48-60. doi: 10.1016/j.gene.2018.01.010

Barišić A, Dević Pavlić S, Ostojić S, Pereza N. Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis. Gene [Internet]. 2018. [pristupljeno 24.12.2024.];647:48-60. doi: 10.1016/j.gene.2018.01.010

A. Barišić, S. Dević Pavlić, S. Ostojić i N. Pereza, "Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis", Gene, vol. 647, str. 48-60, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:500366. [Citirano: 24.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:500366
Podaci o radu
Naslov (engleski)Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta- analysis
AutorAnita Barišić
MBZ: 358963
AutorSanja Dević Pavlić
AutorSaša Ostojić
AutorNina Pereza
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku biologiju i genetiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Genetika, genomika i proteomika čovjeka
Sažetak (engleski)
Matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinase (TIMP) gene polymorphisms have been extensively evaluated as predisposing factors to human reproductive disorders. However, the evidence available is inconsistent. Therefore, we performed a systematic review and meta-analysis to provide the first comprehensive synopsis of case-control studies that investigated the association of MMP and TIMP gene polymorphisms with disorders that influence fertility and pregnancy complications. Literature search was performed using PubMed and Scopus databases. We included 42 case-control studies in the systematic review for the following disorders: adenomyosis, endometriosis, hypertensive disorders of pregnancy, preterm birth and recurrent spontaneous abortion. Although a large number of MMP and TIMP gene polymorphisms were tested, no exclusive and unambiguous risk factors were identified for any of the disorders. The majority of statistically significant associations were confirmed in just one study. Additionally, we performed two meta-analyses for MMP9 rs3918242 polymorphism in endometriosis/adenomyosis and preeclampsia but found no association with either disorder. Considering the modest associations and conflicting results between individual case- control studies, new data is needed for further research of this subject.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaGene
Brojčani podacivol. 647, str. 48-60
p-ISSN0378-1119
DOIhttps://doi.org/10.1016/j.gene.2018.01.010
URN:NBNurn:nbn:hr:184:500366
Datum objave publikacije2018
URL dokumentahttp://bib.irb.hr/917208
URL dokumentahttp://www.sciencedirect.com/science/article/pii/S0378111918300106
Vrsta resursaTekst
Prava pristupaZatvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2018-01-22 18:41:16