prikaz prve stranice dokumenta A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial
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A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial
Therapeutics and Clinical Risk Management, 14 (2018); 741-745. https://doi.org/10.2147/TCRM.S160778
Belavić, Matija; Sotošek Tokmadžić, Vlatka; Brozović Krijan, Antonija; Kvaternik, Ines; Matijaš, Kristina; Strikić, Nedjeljko; Žunić, Josip

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Belavić, M., Sotošek Tokmadžić, V., Brozović Krijan, A., Kvaternik, I., Matijaš, K., Strikić, N. i Žunić, J. (2018). A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial. Therapeutics and Clinical Risk Management, 14., 741-745. doi: 10.2147/TCRM.S160778

Belavić, Matija, et al. "A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial." Therapeutics and Clinical Risk Management, vol. 14, 2018, str. 741-745. https://doi.org/10.2147/TCRM.S160778

Belavić, Matija, Vlatka Sotošek Tokmadžić, Antonija Brozović Krijan, Ines Kvaternik, Kristina Matijaš, Nedjeljko Strikić i Josip Žunić. "A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial." Therapeutics and Clinical Risk Management 14 (2018): 741-745. https://doi.org/10.2147/TCRM.S160778

Belavić, M., et al. (2018) 'A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial', Therapeutics and Clinical Risk Management, 14, str. 741-745. doi: 10.2147/TCRM.S160778

Belavić M, Sotošek Tokmadžić V, Brozović Krijan A, Kvaternik I, Matijaš K, Strikić N, i sur.. A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial. Therapeutics and Clinical Risk Management [Internet]. 04.2018. [pristupljeno 09.05.2024.];14:741-745. doi: 10.2147/TCRM.S160778

M. Belavić, et al., "A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial", Therapeutics and Clinical Risk Management, vol. 14, str. 741-745, Travanj 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:441313. [Citirano: 09.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:441313
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Naslov (engleski)A restrictive dose of crystalloids in patients during laparoscopic cholecystectomy is safe and cost-effective: prospective, two-arm parallel, randomized controlled trial
AutorMatija Belavić
AutorVlatka Sotošek Tokmadžić
AutorAntonija Brozović Krijan
AutorInes Kvaternik
AutorKristina Matijaš
AutorNedjeljko Strikić
AutorJosip Žunić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anesteziologiju, reanimatologiju, hitnu i intenzivnu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Anesteziologija i reanimatologija
Sažetak (engleski)
Purpose: There are no evidence-based guidelines for volume replacement during surgical procedures such as laparoscopic cholecystectomy. However, the administration of a restrictive volume of crystalloids could be more cost-effective and safe. This trial aimed to determine the effectiveness and safety of a restrictive regimen of crystalloids in patients during laparoscopic cholecystectomy by analyzing its cost-effectiveness and 1-year morbidity rate. Patients and methods: In this randomized, prospective study, patients were assigned to one of three groups based on the volume of fluid administered: the restrictive group received 1 mL/kg/hr, the low liberal group received 5 mL/kg/hr, and the high liberal group received 15 mL/kg/hr of Ringer’s solution intraoperatively. There were 40 patients in each group. Each patient’s hemodynamic parameters and laboratory values (arterial blood gas and lactate levels) were measured together with their consumption of crystalloids, volatile anesthetics, and analgesics. Results: Analysis of the hemodynamic and laboratory parameters revealed no signs of global hypoperfusion in any of the groups analyzed. There was no significant difference in the duration of surgery and anesthesia, but the consumption of crystalloids, volatile anesthetics, and opioids was significantly lower in the restrictive group, compared with the low and high liberal groups. Although there was no significant difference in the 1-year morbidity among the groups, heart failure was observed in one patient in the high liberal group in the early postoperative period. Conclusion: Restrictive fluid therapy during laparoscopic cholecystectomy is justified, safe, and more cost-effective than other options.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaTherapeutics and Clinical Risk Management
Brojčani podacivol. 14, str. 741-745
e-ISSN1178-203X
DOIhttps://doi.org/10.2147/TCRM.S160778
URN:NBNurn:nbn:hr:184:441313
Datum objave publikacije2018-04
URL dokumentahttps://doi.org/10.2147/TCRM.S160778
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 3.0 (CC BY-NC 3.0)
Datum i vrijeme pohrane2018-05-07 15:35:04