Chronic Obstructive Pulmonary Disease (COPD) is a multisystem progressive inflammation and pulmonary obstruction. Due to bronchial obstruction, the air flow is reduced, and chronic bronchitis and pulmonary emphysema appear in the disease. Symptoms of illness (chronic cough, dyspnoea and productive coughing) worsen over the years and remain unrecognizable for a long time. Smoking and inhaling harmful gases are the most common causes of chronic obstructive pulmonary disease. Physical examination, history, lung tests, biochemical and microbiological examinations and radiological diagnosis can successfully diagnose COPD. Spirometry is the most important diagnostic method for diagnosing and evaluating the weight of COPD. Differential diagnosis may be difficult because various diseases may have similar symptoms and spirometry results. The most common symptoms are asthma, heart decompensation, bronchiectasis and tuberculosis. By classifying patients in phenotypes, it is possible to better predict the course of the disease, the best therapeutic possibilities and individual access to the patient. Treatment can be pharmacological (bronchodilators, corticosteroids, antibiotics) and non-pharmacological (smoking cessation, pulmonary rehabilitation, education). The Global Initiative for Obstructive Lung Disease (Global Initiative for Obstructive Lung Disease) was the guideline for diagnosis and treatment of this disease. Exacerbations reduce the lung function and quality of life of the patient. It is very important to prevent exacerbation. Comorbidities are very common and poorly affect the prognosis and outcome of the disease. In the early stage diagnosis, the design of the patient care plan, his education and treatment, a family medicine physician is of great importance and responsibility.