Todays a major problem of public health aspect is the COVID-19 pandemic. High infectivity and easy spread has resulted in a high prevalence of this viral disease worldwide. Various measures have been used to control the disease and prevent its spread, among which the most effective are traditional or extraordinary public health measures which include isolation, quarantine, social distance and community restraint. This study describes the appliance, efficiency and complexity of organized (state) quarantine through its organization, selection of the appropriate workers and systematic monitoring of users. The effectiveness of quarantine, in the first place, was interpreted through monitoring the health of users and conducting tests on COVID-19. The organization of quarantine was monitored through technical segments of procedures: selection of a place and a appropriate facility for mobilization; disinfection; waste managmant and disposal of COVID-19-related waste. Appropriate staff are monitored through procedures: users education; access to users and entrance, stay and discharge of the same. The obtained results showed that the organized quarantine led to the successful isolation of suspects and to the prevention of the potential spread of the disease. Also, quarantine requires the necessity of implementation of each procedure and process according to the rules without deviations and human errors in order to prevent further spread of the infection.